Immune System Flashcards
3 types of granulocytes?
- Neutrophils
- Eosinophils
- Basophils
3 types of agrunolocytes?
- B-cells
- T-cells
- Macrophages
Where are B-cells activated by antigens? 2 places
- Lymph nodes
2. Spleen
What are macrophages called in the CNS?
Microglia
What are macrophages called in the skin? 2 names
Langherhans cells = dendritic cells
What are macrophages called in bone?
Osteoclasts
What is defensis?
Antibacterial enzyme on the skin
What is lysozyme?
Antimicrobiaal enzyme in tears and saliva
What are complements?
Proteins that create holes in bacteria
What are the two pathways to activate complements?
- Classical: binding of antibody to pathogen
2. Alternative: does not require antibodies
What are interferons?
proteins that prevent viral replication and dispersion
Which type of immune cells are responsible for flu-like symptons?
Interferons
What cells present MHC I molecules?
All nucleated cells
What are the two roles of macrophages?
- Ingest pathogens and present them on MHC molecules
2. Release cytokines (recruit other immune cells)
What is the difference between MHC I and MHC II molecules?
MHC I: present endogenous pathogens: viruses
MHC II: present exogenous pathogens brought in by endocytosis
By what cells are NK cells activated?
Cells that do not present MHC molecules
What are neutrophils activated by?
bacteria
What does it mean for a bacteria to be opsonized?
It has been tagged with an antibody
What are basophils and mast cells activated by?
Allergens
What is the role of basophils and mast cells?
Inflammatory response
What size and color granules do basophils have?
Large purple
What color granules do Eosinophils have?
Bright red-orange