The Adaptive Immune Response Flashcards
Adaptive immunity
Specificity and memory
Specificity
B and T cells are activated depending on their ability to respond to
the current infection
Memory
lymphocytes will “recall” their first encounter with a pathogen and
respond rapidly to subsequent encounters
Humoral immunity
Mediated by B cells (B lymphocytes)
Cell-mediated immunity
Involves T cells (T lymphocytes)
B-cell receptors
bind free antigens
receptors mature into antibodies
T-cell receptors
bind processed antigens presented to them by other cells
help activate other leukocytes
B cells
stay in the bone marrow
to mature
T cells
mature in the thymus
Maturation:
Developing receptors to recognize specific antigens
Opsonization
process of coating microorganisms or other particles with specific
antibodies so they are more readily recognized by phagocytes
Neutralization
Antibodies coat the surface of microbes or toxins released by
microbes to prevent them from entering cells
T-Cell Receptor
Remains on the T cell surface
Does not get released
2 parallel protein chains
Antigens
not a normal constituent of the body
Lymphatic capillaries
permeate all
parts of the body except the CNS,
bone, placenta, and thymus