Molecular Regulation Flashcards
Repressors:
bind to regulatory sequences in the DNA and
prevent transcription of target genes
Activators:
bind to regulatory sequences in the DNA and
stimulate transcription of target genes
co-repressor
Some must first bind a small ligand (binds to DNA and represses target gene)
inducer
Most must first bind a small ligand (binds to regulatory sequence, removing ligand)
Lac Operon
The Lac Operon is normally off
- In the absence of lactose, the repressor is made and binds at the operator loci
and blocks transcription of downstream structural genes by blocking the
promote
Arg Operon
Arginine Operon
Regulatory gene
encodes a repressor protein that represses (blocks) operon activity
Control Region
Contains promoter (for transcription) and operator, which is where the repressor protein binds
Structural genes
Genes that are regulated together by the regulatory protein and control region
to provide the function of that operon
Repressible
genes in an operon are turned OFF by the product that is synthesized