Testiculaire kanker Flashcards

1
Q

Symptomen testiculaire kanker?

A
  • Pijnloze unilaterale testiculaire massa
  • Scrotale pijn
  • Gynaecomastie
  • Rugpijn en flankpijn door meta’s retroperitoneaal
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2
Q

Vormen van testiculaire kanker?

A

1: kiem cel tumoren:
- Seminoom (SGCT) = komt voort van kiemcellen
- non-seminoom (NSGCT) = komt voort van steunweefsel

2: non-kiem cel tumoren:
- Leydig cell tumoren
- Sertoli cell tumoren

3: secundaire testiculaire tumoren:
- Lymphoma

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3
Q

Wat is zeer belangrijk in de diagnostische work-up van testiculaire kanker?

A

bepaling van serum tumormarkers!

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4
Q

Wat zijn de serum tumormarkers van testiculaire kanker?

A
  • Alfa-foetoproteïne (aFP)
  • Beta-human chorionic gonadotropine (bHCG)
  • lactaat dehydrogenase (LDH)
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5
Q

Tumormerker kenmerken van seminoom (SGCT)

A

beta HCG

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6
Q

Tumormerker kenmerken van non-seminoom (NSGCT)?

A
  • aFP 50-70%

- bHCG 40-60%

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7
Q

BO vermoeden testiculaire tumor?

A
  • Echo
  • MRI

!! Geen biopsie door risico op verspreiding!

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8
Q

Behandeling testiculaire tumor?

A
  • Inguinale orchiectomie (in tunica vaginalis)

- +/- adjuvante chemotherapie en/of radiotherapie

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9
Q

Follow-up testiculaire tumoren?

A
  • Normalisatie tumormerkers
  • RX thorax
  • CT of MRI abdomen
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