Test 4 Anxiolytic and Hypnotic Agent Shi

Question 1

What do benzodiazepines end in?

Answer 1

-pam

Question 2

What are the actions of benzodiazepines?

Answer 2

Acts in limbic system and RAS
Makes GABA more effective

Question 3

What are the indicatioins for benzodiazepines?

Answer 3

Anxiety
Alcohol Disorders
Panic
Restless leg syndrome
Seizures
Insomnia

Question 4

Adverse effects of benzodiazapines

Answer 4

Sedation/ drowsiness
Depression
Lethargy
Blurred Vision
Sleep driving/ weird behaviors
Apathy
Mild paradoxical excitatory reactions
Withdrawel syndrome

Question 5

Drug interactions of benzos

Answer 5

Alcohol: Increased CNS depression
Cimetidine, Oral Contraceptives, Disulfiram: Increase in effect
Theophyllines: Decrease in effect

Question 6

Which benzo is known for restless leg syndrome?

Answer 6

Clonazepam

Question 7

Therapeutic actions of barbiturates

Answer 7

CNS depression
Depress cerebral cortex
Alter cerebellar fx
Depress motor output

Question 8

Indications of barbiturates

Answer 8

Relief of signs and symptoms of anxiety
Sedation
Insomnia treatment
Preanesthesia
Seizure treatment

Question 9

When do barbiturates reach peach level?

Answer 9

20-60 minutes

Question 10

Contraindications of barbiturates

Answer 10

Previous history to addiciton to sedative hypnotic drugs
Latent or manifest porphyria
Marked hepatic impairment or nephritis
Resp distress/ severe resp dysfx
preg

Question 11

Adverse effects of barbiturates

Answer 11

CNS depression
GI
CV
Serious hypoventilation (resp failure)

Question 12

Drug interactions of barbiturates

Answer 12

Alc, antihistamines: CNS
Altered response to phenytoin
MAO inhibitors cause increased serum levels and effect
Decreased effectiveness of oral anticoagulants, digoxin, antidepressants

Question 13

Examples of barbiturates?

Answer 13

Butabarbital
Pentobarbital
Phenobarbital
Secobarbital
-barbital

Question 14

Promethazine uses

Answer 14

Preoperative medication and postoperative to decrease need for narcotics

Question 15

Buspirone uses

Answer 15

Reduces signs and symptoms of anxiety without many of the CNS effects and severe adverse effects
Is less addictive
Better for long term use

Question 16

Dexmedetomidine uses

Answer 16

Sedation of ventilated patients in intensive care of sedtion prior to and/or during surgical procedures

Question 17

Eszopiclone uses

Answer 17

Insomnia

Question 18

Meprobamate uses

Answer 18

Acute anxiety for up to 4 months

Question 19

Ramelteon uses

Answer 19

Insomnia characterized by dificulty with sleep onset

Question 20

Suvorexant uses

Answer 20

Insomnia

Question 21

Tasimelteon uses

Answer 21

Non 24 hour sleep wake disorder

Question 22

Zaleplon and Zolpidem uses

Answer 22

Short term treatment of insomnia