Test 4 Antiparkinson Shi Flashcards
Mnemonic for parkinson meds
ALI Loves Boxing Matches
A- Amantadine
L- Levodopa
B- Bromocriptine
M- MAO Inhibitors
Dopaminergic examples
Amantadine
Apomorphine
Levodopa
Carbidopa Levodopa
Therapeutic action of dopaminergics
Promote dopamine synthesis
Prevent dopamine breakdown
Indicated for relief of symptoms of parkinsons
Contraindications of dopaminergics
Angle closure glaucoma
Levadopa: Pt taking or recently taken MAOI
Cautions: CV disease, Bronchial assma, UT obstructions, Psyciatric disorders
Adverse effects of dopaminergics
CNS
Peripheral efx
Bone marrow depression
Hepatic Dysfx
Drug interactions of dopaminergics
MAOI
OTC vitamins
Carbadopa Levodopa: Iron salts
Rasagiline: Tyramine containing foods, st johns wort, meperidine, acetaminophenc
Levodopa mnemonic side effects
L- Lethargy
E- Euphoria , excessive day time sleepiness
V- Vomit
O- Ortho Hypo
D- Delusion, Delirium, Dryness, Dyskinesia
O- On off phenomenon
P- Priapism, psychosis
A- Athetosis
What’s important when administering sinimet? (Carbadopa- levodopa)
Timing: Adminsiter at regular time intervals with or without food
Avoid high protein meals close to dosing times
What’s important when monitoring sinimet?
Effectiveness: Monitor for improvement in shaking and bradykinesia
Fluctuations: Long term use can cause wearing off effects ; loss of effectiveness before next dose
Ortho Hypo
Neuropsychiatric Symptoms: Confusion, hallucinations, mood changes
What patient education should you give for someone on sinimet?
Medication adherence: Take exactly as prescribed
Dietary: Avoid high protein meals before next dose
Avoid abruptly discontinuiation
Managing side efx: Educate on common side ef like nausea, vom, dyskinesia,
Driving while taking: Don’t drive or operate heavy machinery
What to watch for when someone takes sinimet?
Dyskenisia: Involuntary movements
NV: Common
Ortho Hypo: Impliment fall precautions
Anticholinergic agent examples
Benztropine
Diphenhydramine
Trihexyphenidyl
Indications of anticholinergic agents
Treatment of parkinsons
Relief of symptoms of extrapyramidal disorders associated with some drugs
Contraindications of anticholinergics
Narrow angle glaucoma
GI or GU ostruction
Prostatic hypertrophy
Myasthenia gravis
Tachycardi
Dysrhythmias
hepatic dysfx
Adverse effects of anticholinergic
CNS
Peripheral anticholinergic
Tachy
Palpitations
Hypotension
Adjunctive medications
Entacapone: Increase plasma concentration and duration of action of levodopa
Tolcapone: Further increase levels of levodopa
Safinimide: For patients who are having off episodes
Selegiline: After pt’s show signs of deteriating response to treatment
