Test 3 Diuretic Shi Flashcards
Types of diuretics
Thiazide and Thiazide like diuretics
Loop
Potassium Sparing
Osmotic Diuretics
True or false: Thiazides are first line for hypertension
True
What drugs are thiazide diuretics?
Thiazide: Chlorothiazide
Hydrochlorothiazide
Thiazide like: Chlorthalidone
Indapamide
Metolazone
What do thiazides do ?
Block chloride pump
Keeps chlordie and sodium in tubule to be excreted in urine
Contraindications of thiazides
SLE
Glucose abnormalities (this med raises glucose levels)
Gout: Due to this drug increasing uric acid levels
Liver diease
Hyperperathyroidism
Bipolar disoarder
Adverse effects of thiazides
GI
Hypotension
Hypokalemia
Decreased calcium excretion: Hypercalcemia
Blood glucose may increase
Interactions of thiazides
Digoxin
Quinidine
Antidiabetics
Lithium
Where do loop diuretics work?
Loop of Henle
Types of loop diuretics
Ethacrynic acid
Bumetanide
Furosemide
Torsemide
Indications for loop diuretics
Getting fluid off rapidly and extensive diuresis
Acute HF
Acute PE
Hypertension
Contraindiactions of loop diuretics
Anuria
Hepatic Encephalopathy
Pregnancy
Adverse effects of loop diuretics
Hypokalemia
Alkalosis
Hypocalcemia
Hyperglycemia
Ototoxicity if pushed too fast
Drug interactions of loop diuretics
Aminoglycosides or cisplatin
Anticoagulants
NSAIDS
Digoxin
Lithium
Types of potassium sparing diuretics
Amiloride
Eplerenone
Spironolactone
Triamterene
Indications of potassium sparing diuretics
Pt risk for hypokalemia
Adjunctive treatment of edema
Spironolactone: Drug of choice of hyperaldosteronism
What do osmotic diuretics do?
Pull water into the renal tubule without sodium loss
Pulls large amount of fluids into urine due to osmotic pull
What is the osmotic diuretic?
Mannitol
Indications of osmotic diuretic
Acute situations when necessary to decrease IOP
Increased cranial pressure or acute renal failure due to shock, OD, or trauma
Contraindications for osmotic diuretics
Renal disease
anuria
Pulmonary congestion
Inctracranial bleeding
Dehydration
HF
Adverse effects of osmotic diuretics
HF and PE
Hypotension
CNS tox
