TEST 3 DIABETES Flashcards

1
Q

According to the statistics posted in the ppt posted with this blueprint….Diabetes is the _______ leading cause of death in the US in 2015.

A

7TH

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2
Q

what cells secrete glucagon

A

alpha cells

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3
Q

what cells secrete insulin

A

beta cells

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4
Q

the bodys fuel supply

A

liver

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5
Q

When blood glucose levels fall below normal, as they do between meals, the liver converts stored glycogen back to glucose

A

glycogenolysis.

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6
Q

The liver synthesizes glucose from amino acids, glycerol, and lactic acid in a process called

A

Gluconeogenesis

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7
Q

what 3 body cells cannot use fatty acids and glucose interchangeably for energy

A

brain, nervous tissue, rbc

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8
Q

What are the Counterregulatory Hormones?

A

Catecholamine’s
Growth hormone
Glucocorticoids

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9
Q

work against the action of insulin, raising blood glucose levels in response to hypoglycemia (low blood sugar)

A

Counterregulatory Hormones

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10
Q

Epinephrine:

Stress
Stimulates glycogenolysis
Lipolytic effect on adipose cells

A

Catecholamine’s

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11
Q

Increases protein synthesis

Decreases cellular uptake and use of glucose

A

growth hormone

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12
Q

Critical to survival during periods of fasting and starvation
Stimulate gluconeogenesis by the liver
Cortisol, ACTH
Hypoglycemia is a potent stimulus for cortisol secretion

A

glucocorticoids

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13
Q

due to autoimmune β-cell destruction, usually leading to absolute insulin deficiency

A

type 1

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14
Q

due to a progressive loss of β-cell insulin secretion frequently on the background of insulin resistance

A

type 2

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15
Q

diabetes diagnosed in the second or third trimester of pregnancy that was not clearly overt diabetes prior to gestation

A

gestational diabetes mellitus

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16
Q

All individuals with type 1A diabetes require

A

exogenous insulin replacement

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17
Q

1st clinical manifestation of type 1 diabetes

A

diabetic ketoacidosis

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18
Q

Beta cell destruction with NO evidence of autoimmunity

A

type 1B diabetes

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19
Q

what is the honeymoon phase

A

in type 1 diabetes, their beta cells are still functioning producing insulin so it looks all fine

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20
Q

non insulin dependent diabetes

A

type 2

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21
Q

metabolic abnormalities of type 2

A

insulin resistance,
increased glucose production by the liver,
impaired secretion of insulin by the pancreatic beta cells

22
Q

What are the major factors that predispose a client to Type 2

A

obesity and physical inactivity

23
Q

in type 2 what happens to postpradinal blood levels

A

increases when it should decrease

24
Q

Defined as glucose intolerance that develops during pregnancy and is not clearly overt diabetes

A

gestational diabetes

25
post delivery follow up care for gestational diabetes
evaluated during first postpartum visit with ogtt with 75g glucose load
26
Type 1 diabetes, signs and symptoms
arise suddenly
27
Type 2 diabetes
develops more insidious
28
most common signs and symptoms 3 P
polyuria- excessive urine polydypsia- excessive thirst polyphagia-excessive hunger
29
Recurrent blurred vision Fatigue Paresthesia Skin infections
signs and symptoms of diabetes
30
hemoglobin into which glucose has been incorporated.
Glycosylated Hemoglobin; what a person's average blood glucose level was for the 2 to 3 months before the test. This can help determine how well a person's diabetes is being controlled over time.
31
diabetes management goal
tight glycemic control
32
Hyperglycemia Ketosis Metabolic acidosis
diabetic ketoacidosis characteristics
33
definitive diagnosis of dka
hyperglycemia (blood glucose levels >250 mg/dL [13.8 mmol/L]) low serum bicarbonate low arterial pH positive urine and serum ketones
34
DKA signs and symptoms
``` polyuria polydipsia fruit smell of breath Kussmaul respiration** Metabolic acidosis-acidic. low pH in blood and tissues ```
35
goal in treating DKA
improve circulatory volume decrease blood glucose correct acidosis and electrolyte balance
36
``` Dehydration-Brain cells Thromboembolic events Weakness Polyuria Excessive thirst Neurologic signs and symptoms ```
Hyperglycemic Hyperosmolar State (HHS)
37
Neurologic signs and symptoms of hyperglycemic hyperosmolar state
Babinski reflex Muscle fasciculations Hemianopia
38
treatment of hypoglycemia
rule 15- 15g of glucose can be repeated every 15 minutes for 3 doses
39
a cycle of insulin-induced posthypoglycemic episodes
Somogyi Effect
40
when do the hypoglycemic episodes occur for smoggy effect
at night or at a time when it is not recognized, rendering the diagnosis of the phenomenon more difficult.
41
when does the dawn phenomenon occur
between 5 am and 9 am
42
hot and dry
sugars high
43
cold and clammy
sugars low
44
somoglyi effect and dawn phen happen to whom
type 1
45
type 1 are
body doesn't make insulin
46
type 2
body doesn't respond to the little insulin made
47
associated with diminished perception of vibration, pain, and temperature, particularly in the lower extremities.
somatic neuropathies
48
disorders of sympathetic and parasympathetic nervous system function.
autonomic neuropathies
49
enzymes the pancreas produces
amylase, lipase, protease
50
categories for risk of diabetes
FPG >126 A1C >6.5% random plasma glucose ≥200 mg/dL
51
first manifestation of diabetic neuropathy
increase in urinary albumin excretion, which is defined as a urine protein loss greater or equal to 30 mg/day or an albumin-to-creatinine ratio (A/C ratio) greater or equal to 30 μg/mg (normal <30 μg/mg) from a spot urine collection.