PRE LECTURE 11-16 Flashcards
white blood cells (granulocytes, monocytes, and lymphocytes) are formed in the bone marrow
true
the lifespan of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels
false; short
in neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis
false
infectious mononucleosis is a self-limiting disorder caused by the epstein-barr virus
true
non-hodgkin lymphoma is a form of lymphoma that is associated with the presence of an abnormal cell called a reed-sternberg cell
false; hodgkin lymphoma
common in chronic lymphocytic leukemia, especially in persons with advanced disease
colonial malignancy of B lymphocytes
more children are stricken with WHAT than any other form of cancer, and it is the leading cause of death in children between the ages of 1 and 14 years
ALL; acute lymphocytic leukemia
have a sudden and stormy onset with symptoms of depressed bone marrow function (anemia, fatigue, bleeding, and infections)
acute leukemias
leukemia’s are classified according to their predominant
cell type
chronic myelogenous leukemia is associated with the presence of WHAT, arising from a reciprocal translocation between the long arm of chromosome 22 and the long arm of chromosome 9
philadelphia chromosome
platelets are also known as leukocytes
false; thrombocytes
idiopathic thrombocytopenic purpura is an autoimmune disorder that affects the normal function and formation of platelets
false; results in platelet antibody formation and destruction of platelets
disseminated intravascular coagulation is a condition that results in simultaneous clotting and bleeding
true
the use of aspirin and other non steroidal anti-inflammatory drugs (NSAIDs) has been identified as a cause of impaired platelet function
true
most of the coagulation factors are proteins synthesized in the spleen
false; liver
orderly, stepwise process for stopping bleeding that involves vasospasm, formation of a platelet plug, and the development of a fibrin clot
hemostasis
a decrease in the number of circulating platelets is known as
thrombocytopenia
hemophilia a is an x- linked recessive disorder that involves a deficiency of factor
VIII
used to describe elevations in the platelet count above 1,000,000
thrombocytosis
fat soluble vitamin that is continuously being synthesized by intestinal bacteria, is necessary for normal activity of factors VII, IX, and X and prothrombin
vitamin k
there are two major types of hemoglobin; adult hemoglobin (HbA) and fetal hemoglobin (HbF)
true
sickle cell disease is a chronic disorder that results from changes in the shape, rather than the size of rbc cells
true
iron deficiency anemia only affects infants and toddlers
false ; all ages
the rate at which hemoglobin is synthesized depends on the availability of iron for heme synthesis
true