Test 3 - Ch 12

Question 1

What is paresthesia?

Answer 1

Sx of neuropathic pain where a spontaneous or evoked message arises without stimulation of sensory receptors

Question 2

What is dysethesia allodynia?

Answer 2

Sx of neuropathic pain when an unpleasant sensation arises from a normally non-unpleasant stimulus (sunburn)

Question 3

What is dysethesia secondary hyperalgesia?

Answer 3

Sx of neuropathic pain that arises when pain is out of proportion to stimulus.

Question 4

What are the four mechanisms of neuropathic pain?

Answer 4

ectopic
ephatic
central sensitization
structural reorganization

Question 5

ectopic mechanism of neuro p

Answer 5

sensation is in different location than stimulus
demyelination - peripheral axon killed - central axon collects collateral sprouting - ligand and modality gated -
excessive production

Question 6

ephatic mechanism of neuro p

Answer 6

short circuit from demyelination

tactile AP jumps to P neuron

Question 7

central sensitization mechanism of neuro p

Answer 7

Learn P
strong or long P signal
NS increases receptor for easier transmission
hyperaglesia

Question 8

Structural reorganization mechanism of neuro pain

Answer 8

long and strong
central axon backs off
tactile neuron innervates