Chapter 5 cont. Flashcards
Define passive propagation
spilling of ions from one voltage-gated channel to the next
Active Propagation
AP
Where is the synaptic zone located?
axon hillock
Where is the first place AP is created?
The receptor zone
In a myelinated axon, what is active/passive
node of ranier, myelin sheath
The larger the neuron =
The faster it moves
Increased myelin =
faster
Describe events of a pseudo unipolar cell down a multipolar
local potential (modality-gated) - generation of AP - propagation of Ap - depolarization of presynaptic membrane - release of neurotransmitter - diffusion of neurotransmitter - stimulation of receptors on post synaptic membrane - opening of ion channels - generation of synaptic potential - generation of Ap - propagation of AP - depolarization of presynaptic membrane - release of neurotransmitter….
What is convergence signaling?
many signals all to 1 neuron
Divergence
one signal to many cells
Glia fxs?
enhance signaling provide structure transmission assistance regulate ECF pathogenesis
myelinating GLIA
wrap axons in fatty coating for insulation and increased speed (oligodendrocyte, schwann cell)
oligiodendrocyte
myelin cell of CNS
schwann cell
myelin of PNS - has to have multiple wrapping layers
cleaning/signaling and nourishing GLIA
astrocyte, microglia
What is an astrocyte
glia, cell signaling, scavenger, connects neurons and capillaries, pathway for neurons in development
What is a microglia
Hoover vacuum, phagocyte, abnormal activation could lead to alzheimers
Positive and negative of neuro inflammation
helps clean area of injury - helping tissue heal / harmful fluid from inflammation squeezing brain tissue
Guillain-Barre
peripheral nerves, auto-immune of schwann, removes axon, sensory motor, autonomic, remyelination
MS
oligodendrocytes, sensory, motor, autonomic, remit/relapse, no re-myelination
Glial Tumor
astrocytoma, squeeze/kill brain tissue, frontal is most common, decreases movement and executive funciton
