Test 2 Notes Flashcards
Vaccines
- viruses or bacteria, that are injected into your body in order to stimulate an immune response
- antibodies injected into your body to confer a passive immunity to a specific antigen
Viruses or bacteria, that are injected into your body in order to stimulate an immune response
Vaccines
T-dependent antigens
Must have their antigenic determination sites presented to both B cells and T helper cells before antibody production can occur
Must have their antigenic determination sites presented to both B cells and T helper cells before antibody production can occur
T dependent antigens
After a macrophage consumes a virus, it may:
- incorporate viral antigen determination sites into it’d MHC II makers
- present viral determination sites to B-lymphocytes and T-helper lymphocytes
Which blood type contains anti-B antibodies
Type A and O
Which blood type has no antibodies
AB
Universal donor
Type O
During exposure to an antigen for the first time:
- population of both B lymphocytes and T lymphocytes ar stimulated
- first antibodies produced are in the IgM class
- more than one pop of b-lymphocytes, each with different antigen receptors can be stimulated by the same antigen
T/F: antibodies may link particular antigens together so they cannot function
True
T/F: antibodies may neutralize by coating them, thereby blocking viral blocking viral binding sites and rendering bacterial toxins ineffective
True
T/F: antibodies may link soluble antigens to form an immobile precipitate that is then consumed by macrophages
True
T/F: antibodies may congregate to form pores in the membrane of cellular antigens thereby losing that cell antibodies may activate
False
T/F: antibodies may activate complement which forms an attack complex
True
A women with Rh blood has three children fathered by an Rh+ man. The first child was Rh- and the other two were Rh+, which child is at risk?
Only the third child would be at risk, because, after the mother gave birth to her second child, she may have produced anti-Rh antibodies
Which cells act as presenter cells when they place antigenic determination sites from an antigen on their MHC II markers?
Macrophages, dendritic cells, B-cells
Which cell type acquires IgE from tissue fluids
Plasma
T helper cells secrete —–
Interleukin 4
Antibodies have binding sites for
Specific antigens
Compliment proteins
Macrophages
Define immunocompetence:
The ability to recognize specific antigens
Immunocompetence develops in:
The bone marrow for lymphocytes that will eventually be able to secrete antibodies
Where to t-cytotoxic cells develop?
Thymus
You have reoccurring bouts of certain ailments such as the flu because
The antigen mutates frequently. Thereby rendering ineffective the memory cells produced
Define opsonization
Covering an antigen with antibodies that have macrophage binding sites on their constant regions, thereby facilitating phagocyte action of the macrophage
Low levels of CO2 stimulate
Dilation of bronchioles and vasoconstriction of pulmonary arteries
What do the intercostals and diaphragm do during inhalation
Contract
Dead space:
Contains used air from the alveoli at the end of exhalation
Must be less than the volume of tidal volume in order for alveolar ventilation to occur
Represents an increasingly smaller percentage of TV as exercise and metabolic rate increase
When you LIVE at a high altitude your RBC manufacture:
More 2,3 DPG and this increases the P50 value of the hemoglobin saturation curve
When at a high alt. for a long time, you RBC develop:
A lower affinity to help in unloading O2 at tissues
Define surfactant:
Reduces surface tension in moist alveoli, thereby allowing them to expand when the chest cavity expands during inhalation
Carbon monoxide binds to
The heme of hemoglobin thereby preventing oxygen from binding to hemoglobin
Amount of air remaining in the lungs after a normal exhalation
Functional residual capacity
Location of vocal cords
Larynx
What happens when your metabolizing cells exchange the same number of CO2 and O2 molecules with the systemic blood?
The pO2 of the blood falls more than the pCO2 rises
O2 is less soluble
The total surface area of the small intestine is greater than that of the large intestine because:
- SI is 15x as long as the large intestine
- SI possesses villi
- the surface membranes of the epithelial cells of the small intestine are modified to microvilli