Test 2 (Endocrine Glands) Flashcards
-Regulate organic metabolism and water
-Induce adaptive changes to help body cope
-Promotes sequential growth
-Control reproduction
regulate RBC production
Endocrine system functions
Secrete chemical signals into the blood
Endocrine glands
Chemical signals released into circulation that broadcast throughout the body to every organ
Hormones
Derived from fatty acids/cholesterol
Lipid hormones
Estrogen, progesterone, testosterone, aldosterone
Steroids
Functions in inflammatory response
Prostaglandins
Chains of amino acids
Peptide hormones
Protein bound to one or more carbohydrate group
Glycoprotein hormones
Derived from the AA tyrosine and tryptophan
Amine hormones
Long-chained precursors to hormones (ex insulin produced from proinsulin)
Prohormones
Molecules that are inactive until converted into the active forms of hormones (ex thyroxine secreted)
Prehormones
Occurs when two or more hormones work together to produce a particular effect. Effects may be additive or complementary
Synergistic effects
Occurs when one hormones makes the target cell more responsive to a second hormone
Permissive effects
Occurs when hormones work in opposite directions with the goal of maintaining homeostasis
Antagonistic effects
Increases levels on calcium in the blood if they get too low
PTH
Decreases the release of calcium into the blood if levels are too high
Calcitonin
Stimulates fat storage
Insulin
Stimulates fat breakdown
Glucagon
What controls the secretion of hormones?
Changes in ions or nutrients
Neurotransmitters
Other hormones
What are the hormonal control systems?
- Ions/nutrient concentrations (Humoral Control)
- Neurotransmitters (neural control)
- Hormonal Control
Endocrine cells monitor concentrations of certain ions or nutrients
Humoral control
Neurons from the ANS can influence hormone release from adrenal medulla and other endocrine glands
Neural Control
Neurons from CNS affect hypothalamus, which in turn influences hormone release
Neural Control
Hormone that stimulates the secretion of a second hormone
Tropic hormone
Stimulates and maintains their endocrine target tissues
Tropic hormones
Mechanism of action
- Hormones bind to receptors on or in target cells
- Hormones bind to receptors with a high affinity
- -Hormones can saturate receptors
Hormone receptors are in the cytoplasm or nucleus
Lipophilic hormones
Hormone receptors are on the outer surface of the plasma membrane
Water-soluble hormone receptors
too little hormone
Hyposecretion
Too much hormone
Hypersecretion
Enough hormone, but ineffective response
Hyporesponsiveness
Too much response
Hyperresponsiveness
Defect in the cells that secretes the hormone that is causing problems
Primary secretion disorder
Problem is with too much or to little tropic hormone
Secondary Secretion Disorder