Test 2: antidiarrheal drugs: adsorbents and protectants Flashcards
adsorbents and protectants work by
preventing irritating compounds and bacterial toxins from contacting intestinal mucosa
3 examples of adsorbents and protectants
- activated charcoal
- kaolin and pectin (kaopectate)
- Bismuth subsalicylate
how does activated charcoal work?
it absorbs enterotoxins to its surface
activated charcoal is used when
we know for sure that a toxin was ingested within an hour or two
how do kaolin and pectin (kaopectate) work?
- they absorb enterotoxins
- coat the intestinal bowel wall
- prevent contact between toxin and mucosa
kaolin and pectin (kaopectate) are used when
we’re not sure toxin was ingested, but just in case
kaolin and pectin (kaopectate) doesn’t work as well as
activated charcoal
Bismuth subsalicylate is also known as
Pepto bismol
what does Bismuth carbonate do?
coats the intestinal mucosa
what does Salicylate do?
decreases fluid secretion
Bismuth subsalicylate does what?
decreases intestinal inflammation
Bismuth subsalicylate is not recommended for who?
- why?
cats
- it’s an aspirin compound