quiz 6 NSAIDs pt 2 Flashcards
acetylsalicylic acid is also known as
asprin
acetylsalicylic acid/asprin is commonly used to do what?
prevent the formation of blood clots
acetylsalicylic acid/asprin decreases what?
- by doing what?
platelet aggregation by decreasing thromboxane production
which is metabolized in the liver by binding it with glucuronic acid for elimination?
acetylsalicylic acid/asprin
why do cats metabolize acetylsalicylic acid/asprin slower? (what do they have less of?)
they have less glucuronic acid
animals can use acetylsalicylic acid/asprin to treat
- heartworm - for worms that are dissolving in the CV system
- saddle thrombus
Carprofen, meloxicam are in the group referred to as
Cox-2 inhibitors
why do Cox-2 inhibitors cause less adverse effects than other NSAIDs?
they selectively inhibit the production of prostaglandins associated with inflammation but not other function of the body
Cox-2 inhibitors have minimal effects on
GI tract and kidney
Cox-2 inhibitors have helped dogs with this issue
arthritis
Cox-2 inhibitors have a low incidence of (3)
- liver and renal disease
- hematologic abnormalities (CBCs)
- serious GI disease reported