quiz 6 NSAIDs pt 2 Flashcards

1
Q

acetylsalicylic acid is also known as

A

asprin

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2
Q

acetylsalicylic acid/asprin is commonly used to do what?

A

prevent the formation of blood clots

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3
Q

acetylsalicylic acid/asprin decreases what?

- by doing what?

A

platelet aggregation by decreasing thromboxane production

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4
Q

which is metabolized in the liver by binding it with glucuronic acid for elimination?

A

acetylsalicylic acid/asprin

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5
Q

why do cats metabolize acetylsalicylic acid/asprin slower? (what do they have less of?)

A

they have less glucuronic acid

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6
Q

animals can use acetylsalicylic acid/asprin to treat

A
  • heartworm - for worms that are dissolving in the CV system

- saddle thrombus

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7
Q

Carprofen, meloxicam are in the group referred to as

A

Cox-2 inhibitors

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8
Q

why do Cox-2 inhibitors cause less adverse effects than other NSAIDs?

A

they selectively inhibit the production of prostaglandins associated with inflammation but not other function of the body

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9
Q

Cox-2 inhibitors have minimal effects on

A

GI tract and kidney

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10
Q

Cox-2 inhibitors have helped dogs with this issue

A

arthritis

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11
Q

Cox-2 inhibitors have a low incidence of (3)

A
  • liver and renal disease
  • hematologic abnormalities (CBCs)
  • serious GI disease reported
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