quiz 6 NSAIDs pt 3

Question 1

this drug belongs to a new drug class

Answer 1

Grapiprant

Question 2

how does Grapiprant work

Answer 2

it blocks prostaglandin receptors associated with inflammation ONLY (EP4) - targets inflammation specifically
- just blocks the effect of the prostaglandin, not the production of it

Question 3

why is Grapiprant a good alternative for Cox-2 inhibitors?

Answer 3

Grapiprant isn’t supposed to have an effect on the liver or kidney (it’s safer on them)

Question 4

Grapiprant is to be used in ____ only

Answer 4

dogs

Question 5

Acetaminophen is also known as

Answer 5

Tylenol

Question 6

Acetaminophen/Tylenol provides (2)

Answer 6

• analgesia

- fever reduction

Question 7

Acetaminophen/Tylenol causes no (2):

Answer 7

• GI ulcers

- anti-inflammatory effect

Question 8

adverse effects seen with Acetaminophen/Tylenol overdose (3)

Answer 8

• methemoglobinemia
• Heinz body formation (increases chance of cell being broken down)
• liver tissue destruction

Question 9

what is methemoglobinemia?

Answer 9

blood loses O2 carrying ability/it can’t bind oxygen

Question 10

this (in human medications) is converted into Acetaminophen/Tylenol

Answer 10

phenacetin

Question 11

how much of Acetaminophen/Tylenol will cause toxicity in cats?

Answer 11

single extra dose Tylenol

- 50-60 mg