Test 2: Anti-inflammatories: Dimethyl Sulfoxide

Question 1

Dimethyl Sulfoxide is also known as:

Answer 1

DMSO

Question 2

how does Dimethyl Sulfoxide/DMSO work?

Answer 2

it inactivates superoxide radicals produced during inflammation

Question 3

what are superoxide radicals?

Answer 3

chemical groups that break off from larger molecules when inflammation happens and tissues are falling apart or being damaged -
They seek out covalent bonds of any molecule they can find and causes those molecules to break apart

Question 4

how does Dimethyl Sulfoxide/DMSO help with dealing with superoxide radicals?

Answer 4

DMSO seeks out these radicals to bind them so they’re not able to bind to others and hurt other biological molecules

Question 5

Dimethyl Sulfoxide/DMSO is a gel that can be administered via:

Answer 5

topically or IV

topically, it penetrates intact skin and can be used as a vehicle to carry drugs into the body

Question 6

3 adverse effects of Dimethyl Sulfoxide/DMSO

Answer 6

• erythema
• edema and itching with topical use
• hemolysis with IV admin

Question 7

Dimethyl Sulfoxide/DMSO is available as ______ and ______ grade solvents

Answer 7

medical grade solvent

industrial grade solvent

Question 8

when this drug is mixed with other drugs, it helps:

Answer 8

carry the substances into the body and carry the antibiotic into the SQ tissue

Question 9

Dimethyl Sulfoxide/DMSO smells like:

Answer 9

garlic