quiz 7 antiemetics 2

Question 1

these block nerve transmission through the vagus nerve when there is GI irritation and prevent stimulation of CRTZ

Answer 1

Serotonin receptor agonists

• ondansetron (Zofran)
• dolasetron (Anzemet)

Question 2

these block dopamine receptors in the CNS

Answer 2

Metoclopramide (Reglan)

Question 3

these are seldom used in animals and are used more in humans

Answer 3

Serotonin receptor agonists

• ondansetron (Zofran)
• dolasetron (Anzemet)

Question 4

these work on

• CRTZ
• GI tract receptors
• vomiting center

Answer 4

Serotonin receptor agonists

• ondansetron (Zofran)
• dolasetron (Anzemet)

Question 5

these prevent vomiting caused by CRTZ

Answer 5

Metoclopramide (Reglan)

Question 6

Metoclopramide (Reglan) also acts locally in the GI tract by

Answer 6

• increasing lower esophageal muscle tone (makes it tighter)
• relaxes pylorus
• increases GI motility

Question 7

these prevent vomiting centrally, locally

Answer 7

Maropitant (Cerenia)

Question 8

these are the newest and are now widely used

Answer 8

Maropitant (Cerenia)

Question 9

why is Maropitant (Cerenia) so popular?

Answer 9

it works on many receptors

Question 10

these may cause sedation in dogs, excitement in cats

Answer 10

Metoclopramide (Reglan)

Question 11

these block

• neurokinin-1 receptors in the GI tract
• CRTZ
• vestibular nerve
• vomiting center

Answer 11

Maropitant (Cerenia)

Question 12

these are labeled for used in dogs to prevent vomiting and motion sickness

Answer 12

Maropitant (Cerenia)

Question 13

what other 2 tings is Maropitant (Cerenia) believed to help?

Answer 13

• it can be used as a cough suppressant

- it is believed to have analgesic properties (visceral abdominal)

Question 14

these sting when given SQ, so give it IV slowly

Answer 14

Maropitant (Cerenia)