Taste and Olfaction Flashcards

1
Q

Where does the sensation of taste begin?

A

On taste cells on the tongue

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2
Q

What type of cells are taste cells?

A

Epithelial

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3
Q

Where do taste cells synapse with to send a signal to the brain?

A

Primary gustatory nerve fibers

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4
Q

Taste cells synapse with [insert word] to send signals to the brain.

A

Primary gustatory nerve fibers

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5
Q

Types of papillae?

A
  • Circumvallate
  • Foliate
  • Fungiform
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6
Q

Where are circumvallate papillae located?

A

On the back third of tongue

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7
Q

Where are foliate papillae located?

A

On parallel folds on edges of back of tongue

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8
Q

Where are fungiform papillae located?

A

On the anterior two-thirds of the tongue

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9
Q

True or False?

Each “taste” has distinct chemicals that can bind specific taste receptors.

A

True

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10
Q

True or False?

Taste receptor cells can contain both ion channels or G-protein-coupled receptors (GPCRs).

A

False

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11
Q

Tastes that utilize ion channel signaling are:

A
  • Salty
  • Sour
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12
Q

Tastes that utilize GPCRs include:

A
  • Sweet
  • Umami
  • Bitter
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13
Q

The taste receptor 1 (T1R) family consists of:

A
  • T1R1
  • T1R2
  • T1R3
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14
Q

What macromolecules does the T1R receptor family detect?

A

Sugars and amino acids

(needed for sweet and umami tastes)

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15
Q

The T1R receptor family has a [insert word] extracellular domain.

A

Large

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16
Q

What is the T1R receptor combination for the sweet “taste”?

A

T1R2 and T1R3

17
Q

What is the T1R receptor combination for the umami “taste”?

A

T1R1 and T1R3

18
Q

What is the number of functional T2R receptors in humans? In mice?

A

25, 35

19
Q

The T2R receptor family has a [insert word] extracellular domain.

A

Small

20
Q

True or False?

Each T2R receptor detects only a few bitter compounds with very high affinity.

A

True

21
Q

Types of olfactory receptors include:

A
  • specialists
  • generalists
22
Q

Specialists bind a [insert word] ligands.

A

Few

23
Q

Generalists bind a [insert word] ligands.

A

Lot

24
Q

True or False?

One odor will bind multiple receptors.

A

True

25
Q

Each olfactory neuron expresses how many olfactory receptor genes?

A

One