Takayasu's arteritis Flashcards
What is takayasu’s arteritis?
Chronic granulomatous vasculitis affecting large arteries
What is takayasu’s arteritis?
Large vessel vasculitis
Which vessels are usually affected by takayasu’s arteritis?
The aorta and its main branches.
Who is more commonly affected by Takayasu’s arteritis?
Younger females (e.g. 10-40)
Asian people
What does Takayasu’s arteritis lead to?
Vascular inflammation can cause stenosis, occlusion, and aneurysm formation.
What are the main 2 features of Takayasu’s arteritis?
Absent upper extremity pulse
Discrepancy in blood pressure between the arms (>10 mm Hg)
What are the other possible features of Takayasu’s arteritis?
Night sweats
Arthritis
Myalgia
Skin nodules
Visual defects
Stroke
How can the carotids be affected in someone with
Takayasu’s arteritis?
Carotid bruit and tenderness
Which heart valve defect can occur in someone with
Takayasu’s arteritis?
Aortic stenosis
What complication is associated wth
Takayasu’s arteritis?
Renal artery stenosis
What can be used to diagnose
Takayasu’s arteritis?
vascular imaging of the arterial tree
–Magnetic resonance angiography (MRA)
or
–CT angiography (CTA)
What is used in the management of
Takayasu’s arteritis?
Steroids