Acute Coronary Syndrome Flashcards
What does Acute Coronary Syndrome encompass?
STEMI
NSTEMI
Unstable angina
What is ACS usually due to?
A thrombus from an atherosclerotic plaque blocking a coronary artery
What is a thrombus usually made up of in an artery?
Platelets
Why are antiplatelet medications used to treat ACS?
Thrombi are made up of mostly platelets
What are examples of anti-platelet medications?
Aspirin
Clopidogrel
Ticagrelor
How does ACS cause problems?
Reduces blood flow to the heart
What is reduced blood flow to the heart known as?
Myocardial ischaemia
What is a STEMI due to?
Complete occlusion of the coronary artery
What type of damage does a STEMI cause?
Irreversible damage
What are other names for a STEMI?
Transmural MI
Q Wave MI
What is seen initially on an ECG of someone with a STEMI?
ST elevation
What is seen on an ECG 3 days after someone has had a STEMI?
Q waves
What does a STEMI cause?
Ongoing myocyte death
What is the criteria for diagnosis of a STEMI?
ST elevation
Or new left bundle branch block
What is the management of a STEMI?
Revascularisation within 12 hours
What are the 2 forms of revascularisation?
Primary Percutaneous Coronary Intervention
Thrombolysis
What is primary percutaneous coronary intervention?
Putting a catheter into the patient’s brachial or femoral artery under xray guidance and injecting contrast to identify the area of blockage
Then put a balloon or device to widen gap
What is thrombolysis?
Injecting a fibrinolytic medication that rapidly dissolves clots.
What is the risk associated with thrombolyisis?
The risk of bleeding
What type of intervention is primary percutaneous coronary intervention?
Diagnostic and theraputic