tabletting Flashcards

1
Q

how are plastic materials compressed?

A
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2
Q

what is powder compressibilty?

A
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3
Q

how are elastic materials compressed?

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4
Q

how are brittle material compressed?

A
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5
Q

what are the types of bonds formed during tabletting?

A
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6
Q

what happens during loosely compacted?

A
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7
Q

what happens during linear region?

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8
Q

what happens during maximum compaction?

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9
Q

what happens during excess compression?

A
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10
Q
A

‘lamination reduced tablet strength’

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11
Q

what happens during different dwell times?

A
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12
Q

what happens to tablets during different compressions?

A
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13
Q

what are the tablet defects that can occur?

A
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14
Q

what is brick dust?

A
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15
Q

consequences of problems during formulation?

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16
Q

types of tablet machines?

A
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17
Q

what is a compaction simulator?

A
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18
Q

advantage of using compaction simulator

A
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19
Q

types of coating used for tablets?

A
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20
Q

disadvantage of compaction simulator?

A
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21
Q

how is sugar coating applied?

A
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22
Q

what does the liquid for film coating contain?

A
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22
Q

how is polymer film coating applied?

A
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23
Q

how does the film coat form?

A
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24
Q

common examples of bulking agents?

A
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24
Q

what ae the bulking agents used for tablets?

A
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24
Q

how is a strong tablet formed?

A
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24
Q

purpose of compression aids?

A
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25
Q

desirable characteristics of bulking agents?

A
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25
Q

whats the purpose of bulking agents?

A
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26
Q

example sof compression aids?

A
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27
Q

desirable characteristics of compression aids?

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28
Q

challenges with MCC

A
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29
Q

Microcrystalline Cellulose properties?

A
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30
Q

purpose of disintegrants?

31
Q

common examples disintegrants?

32
Q

challenges of disintegrants?

33
Q

what are the mechanism of disintegrants?

34
Q

why do some tablets disintegrate?

35
Q

example of swelling disintegrant?

36
Q

structure of starch?

37
Q

example of wicking disintegrant

38
Q

example of super disintegrant?

39
Q

what does crosslink do?

40
Q

purpose of lubricants?

41
Q

challenges with magnesium stearate?

42
Q

common types of lurbicants?

43
Q

how is drug dissolution reduced?

44
Q

how are weaker tablets made?

45
Q

what is a flow aid for?

46
Q

common example of flow aids?

47
Q

process of dispersible tablets having a local effect and systemic effect?

48
Q

structure and mechanism of flow aids?

49
Q

types of tablets?

50
Q

why is there a better absorption in the stomach?

51
Q

examples of tablets that rapidly dissolve in the saliva?

52
Q

examples of effervescent tablets?

53
Q

requirements for effervescent tablets?

54
Q

requirements for chewable tablets?

55
Q

formulation design for chewable tablets?

56
Q

what are chewable tablets used for?

57
Q

requires for lozenges?

58
Q

formulation design for lozenges?

59
Q

what are lozenges used for?

60
Q

process of immediate release tablets absorbing in bloodstream?

61
Q

requirements of IR tablets?

62
Q

formulation of IR tablets?

63
Q

packaging of IR tablets?

64
Q

requirements for delayed release tablets?

65
Q

formulation design for delayed released drugs?

66
Q

what are DR tablets used for?

67
Q

process of DR tablets releasing dose?

68
Q

requirements of extended release tablets?

69
Q

formulation design of ER tablets?

70
Q

what are ER tablets used for?

71
Q

how is the drug in ER coated tablets released?

72
Q

different coating for extended release tablets?

73
Q

how are matrix tablets dissolved?

74
Q

different types of matrix coatings?

74
Q

what are the polymers in IR, DR and ER?

75
Q

requirements for vaginal tablets?

76
Q

design and formulation of vaginal tablet?

77
Q

what is the vaginal tablets used for?

78
Q

requirements for buccal and sublingual tablets and lozenges?

79
Q

formulation design of buccal and sublingual tablets and lozenges?

80
Q

what are buccal and sublingual tablets and lozenges used for?