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The Science Of Medicines (PHAR 1021) year 1 > tabletting > Flashcards

tabletting Flashcards

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1
Q

how are plastic materials compressed?

A
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2
Q

what is powder compressibilty?

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3
Q

how are elastic materials compressed?

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4
Q

how are brittle material compressed?

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5
Q

what are the types of bonds formed during tabletting?

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6
Q

what happens during loosely compacted?

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7
Q

what happens during linear region?

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8
Q

what happens during maximum compaction?

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9
Q

what happens during excess compression?

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10
Q
A

‘lamination reduced tablet strength’

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11
Q

what happens during different dwell times?

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12
Q

what happens to tablets during different compressions?

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13
Q

what are the tablet defects that can occur?

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14
Q

what is brick dust?

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15
Q

consequences of problems during formulation?

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16
Q

types of tablet machines?

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17
Q

what is a compaction simulator?

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18
Q

advantage of using compaction simulator

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19
Q

types of coating used for tablets?

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20
Q

disadvantage of compaction simulator?

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21
Q

how is sugar coating applied?

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22
Q

what does the liquid for film coating contain?

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22
Q

how is polymer film coating applied?

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23
Q

how does the film coat form?

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24
Q

common examples of bulking agents?

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24
Q

what ae the bulking agents used for tablets?

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24
Q

how is a strong tablet formed?

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24
Q

purpose of compression aids?

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25
Q

desirable characteristics of bulking agents?

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25
Q

whats the purpose of bulking agents?

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26
Q

example sof compression aids?

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27
Q

desirable characteristics of compression aids?

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28
Q

challenges with MCC

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29
Q

Microcrystalline Cellulose properties?

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30
Q

purpose of disintegrants?

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31
Q

common examples disintegrants?

A
32
Q

challenges of disintegrants?

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33
Q

what are the mechanism of disintegrants?

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34
Q

why do some tablets disintegrate?

A
35
Q

example of swelling disintegrant?

A
36
Q

structure of starch?

A
37
Q

example of wicking disintegrant

A
38
Q

example of super disintegrant?

A
39
Q

what does crosslink do?

A
40
Q

purpose of lubricants?

A
41
Q

challenges with magnesium stearate?

A
42
Q

common types of lurbicants?

A
43
Q

how is drug dissolution reduced?

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44
Q

how are weaker tablets made?

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45
Q

what is a flow aid for?

A
46
Q

common example of flow aids?

A
47
Q

process of dispersible tablets having a local effect and systemic effect?

A
48
Q

structure and mechanism of flow aids?

A
49
Q

types of tablets?

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50
Q

why is there a better absorption in the stomach?

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51
Q

examples of tablets that rapidly dissolve in the saliva?

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52
Q

examples of effervescent tablets?

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53
Q

requirements for effervescent tablets?

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54
Q

requirements for chewable tablets?

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55
Q

formulation design for chewable tablets?

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56
Q

what are chewable tablets used for?

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57
Q

requires for lozenges?

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58
Q

formulation design for lozenges?

A
59
Q

what are lozenges used for?

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60
Q

process of immediate release tablets absorbing in bloodstream?

A
61
Q

requirements of IR tablets?

A
62
Q

formulation of IR tablets?

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63
Q

packaging of IR tablets?

A
64
Q

requirements for delayed release tablets?

A
65
Q

formulation design for delayed released drugs?

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66
Q

what are DR tablets used for?

A
67
Q

process of DR tablets releasing dose?

A
68
Q

requirements of extended release tablets?

A
69
Q

formulation design of ER tablets?

A
70
Q

what are ER tablets used for?

A
71
Q

how is the drug in ER coated tablets released?

A
72
Q

different coating for extended release tablets?

A
73
Q

how are matrix tablets dissolved?

A
74
Q

different types of matrix coatings?

A
74
Q

what are the polymers in IR, DR and ER?

A
75
Q

requirements for vaginal tablets?

A
76
Q

design and formulation of vaginal tablet?

A
77
Q

what is the vaginal tablets used for?

A
78
Q

requirements for buccal and sublingual tablets and lozenges?

A
79
Q

formulation design of buccal and sublingual tablets and lozenges?

A
80
Q

what are buccal and sublingual tablets and lozenges used for?

A

The Science Of Medicines (PHAR 1021) year 1 (20 decks)

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