T9 gas exchange and smoking Flashcards

1
Q

respiratory system consists of

A

nasal and mouth passages
epithelial tubes and tissues of the lungs
muscles of diaphragm and ribcage

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2
Q

goblet cells

A

produce mucus which traps dust and microorganisms

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3
Q

ciliated epithelial cells

A

sweep mucus towards throat to be swallowed

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4
Q

rings of cartilage

A

support the trachea, bronchi and bronchioles

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5
Q

what happens as airway size increases

A

less cartilage and smooth muscle lines the airways

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6
Q

alveolar epithelial cells

A

site for gas exchange in the lungs

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7
Q

trachea

A

transfers air to the lungs

strengthened with cartilage

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8
Q

bronchioles

A

branch from the bronchi and divide into smaller branches as cartilage decreases.

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9
Q

bronchi

A

trachea division into two, supported by the cartilage

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10
Q

are both lungs the same size?

A

no, right is larger than the left

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11
Q

alveoli adaptations

A

large surface area
deflate after each breath out
phospholipid surfactant decreases surface tension and so prevents collapse

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12
Q

surfactant

A

phospholipid produced by type 2 pneumocytyes

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13
Q

gas exchange membrane

A

layered junction between alveolar epithelial cells, capillary endothelial cells, alveolar epithelial cells and basement membranes. gases move freely across this via diffusion

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14
Q

why does the epithelium become thinner in the respiratory zone

A

because the diffusion pathway must narrow in order to increase efficiency of gas exchange.

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15
Q

why is the alveoli and lung tissue made out of elastic tissue

A

as the alveoli requires recoil and expansion in order to assist breathing.

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16
Q

how does ventilation occur

A

antagonistic muscle pairs provide opposing actions in the generation of movement through that of alternate contraction and relaxation

17
Q

examples of antagonistic muscle pairs

A

external and internal intercostal muscles

diaphragm and abdominals

18
Q

inspiration

A

increasing thoracic volume, decreasing lung pressure, drawing air into the lungs
external intercostal muscles and diaphragm contract
ribcage expands and moves up

19
Q

expiration

A

passive process in which external intercostal and diaphragm relax, decreasing thoracic volume and increasing pressure, leads to recoil of lung tissue

20
Q

which muscles assist forced breathing

A

abdominals and internal intercostal muscles

21
Q

COPD

A

chronic obstructive pulmonary disease

persistent inflammatory disease causing obstructed airflow

22
Q

what is COPD

A

permanent damage to the airways, resulting in chronic symptoms and limited treatment
leads to higher risk of heart failure due to lack of oxygen, requires long-term oxygen therapy

23
Q

economic impact of COPD

A

many lost working days

strain on health services

24
Q

personal impact of COPD

A

shortened lifespan, stress on you and family, chronic symptoms require a change in lifestyle

25
risks associated with tobacco smoking
``` COPD nicotine addiction cancer chronic CV and respiratory diseases heart disease increased risk of mouth, throat, lip and lung cancer decreased lung capacity ```
26
lung cancer
uncontrolled growth of epithelial cells
27
chronic bronchitis | symptoms?
excess mucus blocking airways, causing inflammation and infection persistent cough
28
emphysema
narrowing of small airways and lung tissue/ capillary breakdown leads to air pocket formation which decreases gas exchange
29
tar effects
damages teeth and gums desensitises taste buds accumulates in lung tissue dna mutations in the epithelial lung cells >> cell proliferation and tumour formation
30
chronic
having persisted for a long time or constantly recurrent
31
symptoms of COPD
shortness of breath, cough, chronic bronchitis, emphysema,
32
nicotine effects
``` addictive constricts arteries increased BP and HR mobilises fat stores increased metabolic rate ```
33
carbon monoxide effects
toxic displaces oxygen from haemoglobin decreased oxygen content of the blood
34
short-term effects of nicotine
enters bloodstream and reaches brain, stimulating release of messengers that stimulate the reward centre and raises HR/BP brain cell death due to impaired blood flow can result blood vessel constriction drops skin temp rise in CO levels in lungs contributes to breathlessness
35
long term effects of nicotine
increase viscosity of the blood increased risk of fatty plaque build-up in the coronary and carotid arteries increased risk of heart attack/stroke