T Cells

Question 0

IFNg starts up what kind of macrophage?

Answer 0

M1

Question 1

The most important inflammatory cytokine secreted by Th1 cells is…

Answer 1

IFNg

Question 2

What are M1 macrophages characterized by?

Answer 2

being angry and ingesting any bacteria or invading antigen

Question 3

What two cytokines are produced by Th17?

Answer 3

IL17, IL 22

Question 4

What two cytokines induce Th17?

Answer 4

TGFb and IL21

Question 5

What two cytokines are made by Th2?

Answer 5

IL4 IL13

Question 6

What type of macrophages do Th2 cells activate?

Answer 6

M2 macrophages

Question 7

What do M2 macrophages do?

Answer 7

Clear debris and start scar formatin

Question 8

What type of cells does IL 4 recruit?

Answer 8

Eosinophils

Question 9

What type of antibody production do Th2 cells stimulate?

Answer 9

IgE

Question 10

What is the role of follicular helper T cells (Tfh)?

Answer 10

help differentiate the right B cells into plasma cells

Question 11

What type of antibodies are preferentially induced in the spleen? The gut?

Answer 11

Spleen: IgG
Gut: IgA

Question 12

What are the molecular markers expressed on the surface of Treg cells?

Answer 12

CD4, CD25

Question 13

What cytokines are produced by Treg cells?

Answer 13

TGFb and IL10

Question 14

What do Treg cells do?

Answer 14

downregulate other Th cells, prevent autoimmunity

Question 15

What pathway is activated when a CTL binds to a FAS (CD95) ligand?

Answer 15

The latent apoptosis pathway is stimulated

Question 16

What are granzymes and what secretes them?

Answer 16

CTL secrete them

They are lytic granules that have proteases

Question 17

What help granzymes get into the cell?

Answer 17

perforins

Question 18

What activates CTL’s? What converts them to memory cells?

Answer 18

IL-2, IL-21