Molecular Basis of Neoplasia Flashcards
0
Q
What are the four genes that, when damaged, cause a disposition toward a neoplasm?
A
Growth promoting protooncogenes
Growth inhibiting tumor suppressor genes
DNA repair enzymes
Cell death programming regulators
1
Q
The genetic predispositions for cancer fall into what three categories?
A
Autosomal dominant inherited cancer syndromes DNA repair mechanism defects Familial cancer (unknown mechanism)