Molecular Basis of Neoplasia Flashcards

0
Q

What are the four genes that, when damaged, cause a disposition toward a neoplasm?

A

Growth promoting protooncogenes
Growth inhibiting tumor suppressor genes
DNA repair enzymes
Cell death programming regulators

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1
Q

The genetic predispositions for cancer fall into what three categories?

A
Autosomal dominant inherited cancer syndromes
DNA repair mechanism defects
Familial cancer (unknown mechanism)
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