T Cell Intracellular Flashcards by Megan Bradley | Brainscape

Q

Example ?

A

Infection by virus

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Q

What do dendritic cells do?

A

Inside paracortex presents viral antigen bound to MHCI to CD8 cells

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Q

What else can DC do?

A

Induce Th1 response

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Q

How ?

A

Phagocytose viral particles and present them CD4 cells which provide CD8

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Q

What happens next ?

A

CD8 cells provided with IL-2necessary for proliferation and produces chemokines attractive to CD8 cells

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Q

What happens next ?

A

Cytotoxic T cells bind tightly to infected cell and degranulates in the direction of the infected cell

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Q

What is formed ?

A

Polyperforin prores in membrane allowing granules to enter and apoptosis to occur

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