T Cell Extracellular Flashcards
1
Q
Example?
A
Infection by bacteria infections
2
Q
What immunity is triggered ?
A
Antibody mediated
3
Q
What promotes this immunity ?
A
TH2 cells in the exogenous pathway
4
Q
What happens to pathogen?
A
It’s phagotised and placed in vesicle where antigen binds to MHCII proteins
5
Q
What happens to antigen containing vesicle ?
A
Fuses with lysosome where it’s degraded into peptide fragments
6
Q
What happens to MHCII chain complex ?
A
Transported into lysosome where antigen processing takes place
7
Q
What happens to invariant chain?
A
Degraded leaving CLIP in MHCII molecules
8
Q
Where is MHCII transported ?
A
Surface of APC where it awaits recognition by CD4 cells
