Immature Vs Matuew DC Flashcards
1
Q
When are DC in an immature state
A
Prior to encounter with antigen
2
Q
Where are immature DC found?
A
Peripheral tissues such as mucosal tissue
3
Q
What do they express high levels of
A
High levels of PPRs that allow them to recognise PAMPs
4
Q
What do they produce low levels of ?
A
Cytokines
5
Q
What else do they express low levels of ?
A
MHCII molecules on their surface
6
Q
Main function?
A
For antigen capture
7
Q
What do mature DC cells found ?
A
Lymphoid organs such as LN
8
Q
What do they have high expression levels of ?
A
MHC II molecules
9
Q
What do they produce high levels of ?
A
Cytokines such as IL-12
10
Q
Main function?
A
Antigen presentation and T cell activation
