Synaptic Transmission Flashcards

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0
Q

What are gap junctions modulated by?!

A

pH
Calcium ion concentration
Neurotransmitters

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1
Q

What is electrical transmission?!

A

Direct flow of ions from one neurone to another

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2
Q

What is chemical transmission?!

A

Flow of a neurotransmitter

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3
Q

What is central synapse an example of?!

A

Chemical transmission

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4
Q

Does chemical or electrical transmission have cytoplasmic continuity?!

A

Electrical

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5
Q

Which out of electrical and chemical transmission has a synaptic delay?!

A

Chemical

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6
Q

Which transmission is unidirectional?!

A

Chemical

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7
Q

What is the criteria for a chemical messenger to be classes as a NT?!

A

Synthesised in the neurone
Present in the presynaptic neurone
Mimics a endogenously released transmitter if applied exogenously
Has a specific removal mechanism

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8
Q

Where are peptides synthesised?!

A

Cell body

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9
Q

Where are amines and amino acids synthesised?!

A

Synaptic terminal

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10
Q

What are the two types of synaptic vesicles?!

A

Small clear

Large dense

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11
Q

In synaptic vesicle cycling where are the vesicles targeted?!

A

Active zones

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12
Q

What does a rise in calcium ions cause?!

A

Vesicles fuse and release their contents

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13
Q

How is the fused vesicle membrane taken up into the cell?!

A

Endocytosis

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14
Q

What are the names of the two SNARE proteins?!

A

Synaptobrevin

Synaptotagmin

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15
Q

What is synaptobrevin?!

A

A vesicle bound protein which binds with SNAP-25 on the plasma membrane = vesicle docking and priming

16
Q

What is synaptotagmin?!

A

A calcium ion sensor

Causes fusion

17
Q

What are end plate potentials?!

A

Action potential dependent release of large numbers of vesicles
Multiples of MEPPs

18
Q

What are miniature end plate potentials?!

A

Result of spontaneous release of a single vesicle (quanta) containing thousand of molecules of neurotransmitter

19
Q

What can spatial summation prevent?!

A

Action potential firing