Synapses Flashcards
What is a synapse?
a junction between a neurone and another neurone or neurone and effector cell
What happens when action potential reaches synaptic knob?
presynaptic membrane depolarises causing calcium ion channels to open and the Ca+ ions diffuse into presynaptic knob. This causes vesicles containing neurotransmitters to fuse with pre synaptic membrane and are released into synaptic cleft via exocytosis
What happens to neurotransmitter in synaptic cleft?
it binds to receptors on postsynaptic membrane
What happens in postsynaptic neurone after neurotransmitter has bound to receptors?
sodium ion channels open and sodium ions diffuse in causing an action potential on other side of synapse
What happens after action potential is triggered in postsynaptic neurone?
enzymes release neurotransmitter from receptors and breaks it down and returns it to presynaptic knob. This prevents response happening again and again
What are the roles of synapses?
ensuring impulses are unidirectional, allows an impulse to be transmitted from one neurone to a number of neurones and a number of neurones can transmit impulses into a single neurone.
What is summation?
The sum total of lots of smaller impulses triggers an action potential as neurotransmitter builds up so that threshold value it met
What are the two types of summation?
spatial - multiple presynaptic neurones connect to one postsynaptic neurones
temporal - a single presynaptic neurone releases lots of neurotransmitter as a result of several action potentials action potentials arriving in quick succession
What are the two types of neurotransmitter?
excitatory and inhibitory
What does an inhibitory neurotransmitter do?
causes hyperpolarisation of post synaptic neurone which prevents an action potential