SUGAR & INSULIN Flashcards

1
Q

What hormone stores glucose in adipose tissue?

A

Insulin

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2
Q

Decreased insulin will result in what?

A

increased gluconeogenesis

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3
Q

what is phosphorylated in an insulin receptor?

A

tyrosine

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4
Q

what needs a protein transporter to cross the cell membrane?

A

Glucose via GLUT 4 FAC BIDIRECTIONAL TRANSPORTATION

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5
Q

Glucagon signals through?

A

cAMP (intercellular 2nd messenger)

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6
Q

Glucagon receptor is a __________ coupled to a ___________

A

7-transmembrane receptor coupled to a G-protein + cAMP

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7
Q

What is intracellular element of glucagon?

a. cAMP
b. AMP
c. ATP
d. ADP

A

a. cAMP

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8
Q

What do Glucagon & epinephrine both/have in common?

A

Glycogenolysis + GLUCEONEOGENESIS

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9
Q

Oxidative phosphorylation occurs in what enzyme?

A

Pyruvate dehydrogenase

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10
Q

What enzyme is used for decarboxylation?

A

pyruvate decarboxylase

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11
Q

rate limiting enzyme for glycosis?

A

phosphorfructokinase (PFK)

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12
Q

What is not found in msucles?

A

Glucose-6-phosphate

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13
Q

Glucose is sequestered by which enzyme

A

Hexokinase

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14
Q

What is not true regarding hexokinase & glucokinase?

A

they have same KM glucokinase is higher, more affinity

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15
Q

Describe Glucokinase

A

a soform of hexokinase found only in the liver & only uses substrate glucose

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16
Q

UTP-Glucose reacts with which of the following in glycogen synthesis

A

Glucose-1-Phosphate

17
Q

What steps restores oxaloacetate in TCA?

A

Malate, malate dehydrogenase

18
Q

What enzymes produce oxaloacetate?

A

Pyruvate Carboxylase (pyruvate–> oxaloacetate)

19
Q

What is the main source of Glycerol?

A

Glucose/ pyruvate

20
Q

Where is phosphoenolpyruvate found?

A

Liver