SUGAR & INSULIN Flashcards
What hormone stores glucose in adipose tissue?
Insulin
Decreased insulin will result in what?
increased gluconeogenesis
what is phosphorylated in an insulin receptor?
tyrosine
what needs a protein transporter to cross the cell membrane?
Glucose via GLUT 4 FAC BIDIRECTIONAL TRANSPORTATION
Glucagon signals through?
cAMP (intercellular 2nd messenger)
Glucagon receptor is a __________ coupled to a ___________
7-transmembrane receptor coupled to a G-protein + cAMP
What is intracellular element of glucagon?
a. cAMP
b. AMP
c. ATP
d. ADP
a. cAMP
What do Glucagon & epinephrine both/have in common?
Glycogenolysis + GLUCEONEOGENESIS
Oxidative phosphorylation occurs in what enzyme?
Pyruvate dehydrogenase
What enzyme is used for decarboxylation?
pyruvate decarboxylase
rate limiting enzyme for glycosis?
phosphorfructokinase (PFK)
What is not found in msucles?
Glucose-6-phosphate
Glucose is sequestered by which enzyme
Hexokinase
What is not true regarding hexokinase & glucokinase?
they have same KM glucokinase is higher, more affinity
Describe Glucokinase
a soform of hexokinase found only in the liver & only uses substrate glucose