CHOLESTEROL / LIPIDS Flashcards
1
Q
De novo cholesterol involves everything except?
A
Oxygen (needs ATP, NADPH, acetyl CoA, malonyl CoA)
2
Q
Acetyl CoA carboxylase enzyme of fatty acid synthesis. Function?
A
function is to provide malonyl CoA subsrtate for biosynthesis of fatty acids
3
Q
Rate limiting step of cholesterol biosynthesis?
A
HMG CoA Reductase
4
Q
Statin drugs are?
A
HMG- CoA reductase inhibitors
5
Q
How do animal cells primarily use cholesterol?
A
Cell membrane
6
Q
Aside from phospholipid, cholesterols is the ?
A
most important cell membrane component
7
Q
LDL Receptor
A
APOB-100 (apolipoprotein B)
8
Q
Triglyceride is carried from the liver to organs by?
A
chylomicrons
9
Q
Hyperlipidermia: fat in blood; chylomicrons
A
liver–> VLDL–> blood–> tissue–> LDL–> HDL
