Substance-Related and Addictive Disorders Flashcards
The ingestion of psychoactive substances in moderate amounts that does not significantly interfere with social, educational, or occupational functioning
Substance use
The experience of significantly maladaptive behavioral and psychological symptoms due to the effect of a substance on the central nervous system that develops during or shortly after use of the substance
Intoxication
A category of psychological disorders in which drugs are used to such an extent that behavior becomes maladaptive, social and occupational functionining are impaired, and control or abstinence becomes impossible
Substance use disorders
How many symptoms are required to meet the criteria for substance use disorder?
At least 2 symptoms
How long should symptoms persist to meet the criteria for substance use disorder?
At least 12 months
The use of a drug that is accompanied by a physiological dependence on it, made evident by tolerance and withdrawal symptoms
Addiction
The need for increased amounts of a substance to achieve the desired effect and a diminished effect with continued use of the same amount
Tolerance
Severely negative physiological reaction to the removal of a psychoactive substance, which can be alleviated by the same or a similar substance
Withdrawal
Maladaptive pattern of substance use characterized by:
- The need for increased amounts to achieve the desired effect
- Negative physical effects when the substance is withdrawn
- Unsuccessful efforts to control its use
- Substantial effort expended to seek it or recover from its effects
Substance dependence
Maladaptive pattern of substance use leading to significant distress or impairment in social and occupational roles and in hazardous situations
Substance abuse
Psychoactive substances that result in behavioral sedation and that slow the nervous system
Depressants
A depressant byproduct of the fermentation of yeasts, sugar, and water
Alcohol
Pattern of alcohol use whereby the individual has at least 5 drinks in a short period of time
Binge drinking
Pattern of alcohol use whereby the individual has at least 5 drinks on the same occasion at least 5 times in a 30-day period
Heavy-use drinking
Amnesia for the events that occurred while one was intoxicated
Blackout
How does alcohol affect GABA receptors?
It inhibits GABA receptors, which may account for its ability to reduce tension.
How does alcohol affect glutamate receptors?
Alcohol inhibits glutamate receptors, which may cause slowed thinking and memory loss.
How does alcohol affect serotonin and dopamine?
Alcohol increases serotonin and dopamine levels.
A condition referring to a Vitamin B deficiency resulting from chronic alcohol abuse, whereby the individual suffers severe loss of memory wherein memory gaps are filled in by reporting imaginary events (confabulation)
Amnestic syndrome
A condition characterized by frightening hallucinations and body tremors that result when a heavy drinker withdraws from alcohol
Delirium tremens (withdrawal delirium)
An organic brain syndrome resulting from prolonged heavy alcohol use and consequent thiamine deficiency, accompanied by symptoms of confusion, unintelligible speech, and loss of motor coordination
Wernicke-Korsakoff syndrome
A pattern of problems defined by retarded growth of the developing fetus and infant involving cranial, facial, and limb anomalies and intellectual disabilities that result from heavy drinking by the victim’s mother during pregnancy
Fetal alcohol syndrome (FAS)
Enzyme that helps humans metabolize alcohol
Alcohol dehydrogenase
The misuse of more than 1 drug at a time
Polydrug abuse
How are alcohol and nicotine cross-tolerant?
Nicotine can induce tolerance for the rewarding effects of alcohol, and vice versa.
Gene that produces a severe flushing effect (reddening and burning of the face) after drinking alcohol
Aldehyde dehydrogenase (ALDH2) gene
Impairment in cognitive processing from drinking alcohol that narrows attention to the most immediately available cues
Alcohol myopia
What are the 4 stages of alcoholism?
- Pre-alcoholic stage
- Prodromal stage
- Crucial stage
- Chronic stage
State at least 1 medication commonly prescribed to reduce alcohol cravings.
- Naltrexone
- Acamprosate
A drug that prevents the breakdown of acetaldehyde (a byproduct of alcohol), thereby producing nausea, vomiting, and elevated heart rate and respiration
Disulfiram
State at least 3 psychotherapy approaches used to treat alcohol use disorder.
- Aversive therapy
- Behavioral couples therapy
- Cognitive therapy
- Contingency management therapy
- Motivational interventions
An interview used in motivational interventions that carefully assesses drinking in the past 3 months
Timeline Follow Back (TFLB)
An organization that is founded on the notion that alcoholism is a disease and that alcoholics must acknowledge their addiction
Alcoholics Anonymous (AA)
An approach to alcohol consumption that avoids the extremes of total abstinence and inebriation
Controlled drinking
Sobell’s current approach to moderate alcohol consumption based on the assumption that people have more potential control over their drinking and that heightened awareness of the costs of drinking excessively - as well as of the benefits of cutting down - can be of material help
Guided self-change
What neurotransmitter system is impacted by sedative, hypnotic, and anxiolytic drugs?
GABA
Also known as liquid ecstasy, a depressant approved for the treatment of narcolepsy tht can produce a state of relaxation at low doses
Gamma-hydroxybutyric acid (GHB)
Substances that elevate mood, activity, and alertness by activating the nervous system
Stimulants
Stimulants used to treat hypersomnia and narcolepsy by helping the release of norepinephrine and dopamine and blocking their reuptake, thereby making more of them available throughout the system
Amphetamines
The first amphetamine synthesized in 1927 that was used as an inhalant to relieve stuffy nose
Benzedrine
The practice of injecting amphetamines frequently over several days without eating or sleeping
Speed run
A drug with stimulant effects and occasional hallucinogen-like properties that is made from MDMA, which is chemically similar to mescaline and amphetamines
Ecstasy
An amphetamine initially used as an appetite suppressant for WWI soldiers that is derived from precursors found in nutmeg, dill, saffron, and sassafras
Methylene-dioxymethamphetamine (MDMA)
A variation of MDMA that has been marketed as a purified powder in capsules
Molly
What neurotransmitter is affected by ecstasy?
Serotonin
Ecstasy acts primarily by contributing to both the release and the subsequent reuptake of serotonin.
A purified, crystallized form of amphetamine that is smoked and that causes marked aggressive tendencies
Methamphetamine
True or False: Methamphetamine stays in the system longer than cocaine.
True
A variation of methamphetamine in cleaar crystal form
Crystal meth (ice)