Study Guide Unit 3 Flashcards
Function of the valves
Valves prevent back flow of blood. They allow blood to move one way through the heart and body.
Know how systemic circuit differs from pulmonary circuit.
a. Systemic circuit- much longer, higher workload, larger blood volume, higher pressure.
b. Systemic arteries carry oxygenated blood, veins deoxygenated.
c. Pulmonary arteries carry deoxygenated blood and vein carry oxygenated blood.
Coronary circuit
a. Coronary circulation supplies the heart wall.
b. Coronary arteries bring oxygenated blood to myocardium.
c. 2 coronary arteries.
d. Coronary veins collect deoxygenated blood and drain it into the coronary sinus.
Fetal circulation. What is the difference between fetal circulation and circulation after birth?
a. During fetal development the lungs do not function so there is more pressure on the right side of heart. After birth when lung’s function pressure increases on the left side of heart and actually causes more pressure to be on the left side of heart then on the right side of heart.
5 phases of cardiac cycle
atrial systole, early ventricular systole, late ventricular systole, early ventricular diastole, late ventricular diastole
Atrial systole:
atria contracted, and ventricles relaxed, moves remaining blood from atria to ventricles, AV valves open, semilunar valves closed.
Early ventricular systole
beginning of ventricular contraction, ventricular pressure increased more than atrial pressure, AV valves closed-first heart sound is heard, semilunar valves are still closed ventricles should generate more pressure to open them
Late ventricular diastole
atria relaxed, and ventricles contracted, ventricular pressure increases, semilunar valves open, blood ejection termed ventricular ejection
Early ventricular diastole
atria relaxed, and ventricles relaxed, ventricular pressure decreases, blood flowing backward slightly (caught in semilunar valves, which close-second heard sound is heard-S2), prevents backflow into ventricles
Late ventricular diastole
atria relaxed, and ventricles relaxed, ventricular pressure decreased, atrial pressure increased, semilunar valves remain closed, most ventricular filling occurs (70% of EDV)
Cardiac output: definition, CO (CO=SV x HR). factors that affect it (heart rate, SV)
Cardiac output is the amount of blood ejected per set amount of time (usually a minute) This is affected by the stroke volume (average is usually 70 CC) and Heart Rate.
Positive chronotropic agent
(increase cardiac output): sympathetic stimulation-norepinephrine, thyroid hormone, nicotine, and cocaine.
Negative chronotropic agents
(decrease cardiac output): parasympathetic innervation- acetylcholine, beta-blocker.
Know main factors that affect SV
preload, afterload, contractility
Stroke volume
amount of blood ejected in one beat.
Preload
filling time (lower filling time lower EDV, higher filling time higher EDV), venous return (blood volume, H2O, and position).
Contractility
Increased contractility increased stroke volume, decreased contractility decreases stroke volume
Afterload
increases afterload decreases stroke volume, decrease afterload increases stroke volume
Plasma components
92% water. 8% dissolved molecules and ions
Main plasma protein
Albumins
Globulins
Fibrogens
Albumins
Maintain osmotic pressure
Globulins
(alpha and beta transport) (gamma antibodies produced by lymphocytes).