Structure and Function Flashcards
What are the 2 multiaxial joints?
Shoulder and hip; ball and socket joints that allow movement about all 3 perpendicular axes
How many neuromuscular junctions are there in a muscle cell?
One
What is a motor neuron and the muscle fibers it innervates called?
Motor unit
What is sarcoplasm?
Cytoplasm of the muscle cell
Two types of myofilaments that make up a myofibril in the muscle cell?
Myosin and actin
Which myofilament forms the crossbridge in the muscle cell?
Myosin
What is the smallest contractile unit of skeletal muscle?
Sarcomere; repeated the entire length of the muscle fiber
A band
Corresponds to the alignment of myosin filaments
I band
Light area; corresponds to the area of 2 adjacent sarcomeres that only contain actin
Z line
Thin dark line in the middle of the I band
H zone
Area in the center of the sarcomere where only myosin is present
What mineral is released into the muscle cell when an action potential is discharged?
Calcium
Sliding Filament Theory of Muscle Contraction
Calcium binds to troponin (on actin); the myosin crossbridges attach to actin and pull the actin towards the center of the sarcomere
Steps of Muscle Contaction
- ATP binds to myosin head and is split by myosin ATPase which puts the myosin head in an energized state and allows it to bind to move into position and bind with actin
- Release of phosphate from ATP causes the myosin filament to change shape and shift
- This pulls the actin filament towards the center of the sarcomere and is referred to as the power stroke; ADP is then released
- A new ATP must bind to myosin in order for it to detach from actin; move back to its original position; and repeat the process
- Cycle continues as long as ATP and ATPase are present and calcium is bound to troponin
What determines the force production of a muscle?
The number of crossbridges that are formed between actin and myosin at any instant in time