STIs Flashcards

1
Q

which 2 STIs are tested for together (same test)

A

chlamydia and gonorrhea

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2
Q

which test is used for chlamydia and gonorrhea

A

NAATs or PCR

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3
Q

what collection method is used for chlamydia and gonorrhea in males

A

first pass urine

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4
Q

what collection method is used for chlamydia and gonorrhea in females

A

vulvovaginal swab

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5
Q

after treatment complete for an STI, how long should you abstain from sex for

A

abstain for 1 week - condoms not 100% effective

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6
Q

normal vaginal flora

A

lactobacillus

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7
Q

what is the most common STI

A

chlamydia

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8
Q

what category of chlamydia causes STIs

A

chlamydia trachomatis D-K

DicK

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9
Q

what category of chlamydia causes trachoma eye infection

A

Chlamydia trachomatis A-C

then you cant see (C)

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10
Q

what category of chlamydia causes lymphogranuloma venereum (LGV)

A

chlamydia trachomatis L1-L3

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11
Q

which group of people get lymphogranuloma venereum

A

MSM (men who have sex with men)

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12
Q

presentation of chlamydia in females

A

asymptomatic
intermenstrual bleeding
lower abdo pain
painful sex

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13
Q

presentation of chlamydia in males

A

asymptomatic
painful peeing
watery urethral discharge

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14
Q

which test do you do for chlamydia

how is it sampled

A

PCR or NAATs

first pass urine in males
vulvovaginal swab in females

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15
Q

does chlamydia culture

A

no, hence need to do PCR/NAATs

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16
Q

which do you do first pass urine and not midstream urine when testing for chlamydia/gonorrhea in males

A

first pass = more likely to catch the bacteria

midstream = used for UTIs

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17
Q

why don’t you do endocervical swabs for chlamydia/gonorrhea in females

A

would get same result as vulvovaginal but is more invasive (cant do it themselves)

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18
Q

management of chlamydia

A

first line - doxycycline 100mg BD 7 days

second line - azithromycin 1g PO - only take once

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19
Q

complications of chlamydia

A

pelvic inflammatory disease (PID) = tubal damage and infertility

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20
Q

is chlamydia or gonorrhea more common

A

chlamydia

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21
Q

what is the most common STI in MSM

A

gonorrhoea

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22
Q

which bacteria causes gonorrhea

what is its gram stain

A

Neisseria gonorrhea

Gm-ve diplococci

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23
Q

how does gonorrhea present in males

A

dripping pus

dysuria (painful peeing)

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24
Q

how does gonorrhea present in females

A

white vaginal discharge
vulvar irritation
dysuria (painful peeing)

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25
which test do you do for gonorrhea how is it sampled
PCR or NAATs first pass urine in males vulvovaginal swab in females
26
if someone presents to GP with gonorrhea what do you do
refer to sexual health
27
management of gonorrhea
IM ceftriaxone | + ?azithromycin for chlamydia??
28
what do you need to do 5 weeks after gonorrhea has been treated
test of cure - repeat PCR/NAATs to ensure infection has gone
29
why do you nee to do a test of cure after gonorrhea has been treated
high antimicrobial resistance
30
where else is gonorrhea common (other than STI)
gonococcal pharyngeal infection
31
who gets gonococcal pharyngeal infections
MSM (from oral sex)
32
what bacteria causes syphilis
treponema pallidum
33
how does the primary early infectious stage of syphilis present
painless chancre/ulceration
34
how does the late non-infectious stage of syphilis present
it is latent
35
how does the secondary early infectious stage of syphilis present
rash on soles of feet/hands 'great imitator' - generic rash
36
painless penile ulcer/chancre
syphilis primary stage
37
painful penile ulcer/chancre
HSV = genital herpes
38
treponema pallidum
syphilis
39
diagnostic test for syphilis
PCR
40
what does syphilis look like on PCR
spirals
41
screening test for syphilis
IgM and IgG ELISA
42
tests for syphilis to measure response to therapy (by monitoring inflammation)
VDRL | RPR (rapid plasma regain)
43
management of syphilis
first line - penicillin long acting IM | second line - doxycycline
44
why might someone with syphilis accidentally treat themselves
syphilis is treated with penicillin = used for lots of things
45
what type of herpes simplex virus causes STIs
HSV1 or HSV2
46
which type of HSV causes cold sores
HSV1
47
which type of HSV has more viral shedding (more expulsion of virus after replication)
HSV2
48
which microorganism causes genital herpes
HSV
49
presentation of genital herpes
``` asymptomatic painful blisters (= ulceration) dysuria vaginal discharge 'strawberry vagina' from inflammation ```
50
'strawberry vagina'
genital herpes (HSV) strawberry vagina from inflammation
51
testing method for genital herpes how do you get sample
PCR (bc virus) deroof blister - ie needs to be symptomatic to sample
52
which STI is recurrent (not curable) how does it present upon recurrence
genital herpes (HSV) less severe than initial infection when it recurs
53
management for genital herpes
``` probs nothing, just symptomatic acyclovir PO (bc virus) - doesn't always work ```
54
symptomatic management of genital herpes
topical lidocaine - pain relief saline bath pee in bath/shower
55
which micro organism causes genital warts
HPV 6 + 11
56
is there a connection between genital warts and cervical cancer
no - need to reassure patient HPV 6+ 11 causes genital warts HPV 16 + 18 causes cervical cancer
57
cauliflower appearance
genital warts (HPV)
58
is genital warts (HPV) painful
no
59
presentation of genital warts
painless | cauliflower appearance
60
diagnosis of genital warts
clinical diagnosis - don't need biopsy
61
management of genital warts
nothing | cryotherapy
62
does HPV vaccine cover against genital warts
yes! | covers 6, 11, 16 + 18
63
which microorganism causes vaginal thrush
candida albicans
64
what type of microorganism is candida albicans (causes vaginal thrush)
fungi
65
presentation of vaginal thrush
intense vaginal itch | white vaginal discharge
66
diagnosis of vaginal thrush
clinical diagnosis
67
risk factor for vaginal thrush
uncontrolled diabetes
68
management of vaginal thrush
symptomatic only! not curative (bc not an STI) topical clotrimazole - OTC antifungal cream keep area clean/cool/dry
69
is vaginal thrush an STI
no
70
how does candida balanitis present on penis
spotty rash
71
fish smelling discharge frothy bubbles brown discharge
bacterial vaginosis
72
fish smelling discharge differentials (2) which is more common how do they differ
bacterial vaginosis - more common trichomonas vaginalis trichomonas = itch, inflammation (red) bacterial vaginosis = no itch, no inflammation (red)
73
which microorganism causes bacterial vaginosis
gardnerella vaginalis
74
'clue cells' on microscopy
bacterial vaginosis
75
bacterial vaginosis management
metronidazole 7 days
76
is bacterial vaginosis an STI
no
77
is trichomonas vaginalis an STI
yes
78
which 2 vagina problems are treated with metronidazole
bacterial vaginosis trichomonas vaginalis both also present with fishy discharge!
79
what type of microorganism does metronidazole treat
anaerobe (hence bacterial vaginosis and trichomonas vaginalis)
80
what type of microorganism is trichomonas vaginalis
parasite
81
what does trichomonas vaginalis look like on microscopy
it moves ! bc parasite aka flagellated protozoa (has a tail)
82
investigation for trichomonas vaginalis how is the sample collected
wet film microscopy from vaginal swab
83
``` fish smelling discharge bubbly vaginal irritation (sore) strawberry cervix (form irritation) ```
trichomonas vaginalis diff from bacterial vaginosis bc irritation bc infection (STI)!
84
strawberry cervix
trichomonas vaginalis
85
management of trichomonas vaginalis
PO metronidazole same as bacterial vaginosis
86
management of phthirus pubis (pubic lice)
malathion lotion (to sooth itch)