Male hypogonadism Flashcards
primary causes of male hypogonadism
klienfelters XXY
Y chromosome deletions
radiotherapy
androgen insensitivity syndrome
= problem with testes
what is androgen insensitivity syndrome
when testes develop but don’t descend = present as female
secondary causes of male hypogonadism
pituitary disease
hypothalamic disease eg anorexia
= problem higher up than testes eg pituitary/hypothalamus
presentation of male hypogonadism
no puberty, ask about shaving
loss of sexual function
infertility
reduced testicular volume
bc you need LH and FSH to make testosterone and sperm
investigation results for primary hypogonadism (hypergonadotropic hypogonadism)
testosterone, LH and FSH levels
testosterone low
LH high
FSH high
hypergonadotropic bc LH and FSH are high
investigation results for secondary hypogonadism (hypogonadotropic hypogonadism)
testosterone, LH and FSH levels
testosterone low
LH low
FSH low
hypogonadotropic bc LH and FSH are low
treatment of male hypogonadism
testosterone replacement therapy in men <50 (if >50 it has comorbidities and probs not useful)
what screening do you need to give someone with testosterone supplementation
prostate screening
what thing doesn’t get fixed when you give a man with hypogonadism testosterone
fertility
