STIs Flashcards
what causes syphilis?
treponema pallidum
signs of primary syphilis?
painless chancre at site of inoculation
features of secondary syphilis?
lymphadenopathy
alopecia
condylomata lata
rash on palms and soles
if patient has a lesion, what Ix should be done?
dark field microscopy
what two blood tests are done to confirm syphilis?
serum trepenomal EIA (screening)
serum TPPA
what are present during infection and for life in syphilis?
serum trepenomal EIA
serum TPPA
IgM acute, IgG for life
Tx for syphilis?
IM benzylpenicillin
for syphilis, what can be measured to see if Tx is working?
rapid plasma reagin
complications of syphilis?
CVS
neuro deficits
what types of HPV cause genital warts?
6 and 11
what types of HPV are assoc with cancer?
16 and 18
what type of HPV is assoc with palmar/plantar warts?
1 and 2
what Tx is given for HPV?
imiquimod (topical)/podophyllotoxin
cryotherapy
electrocautery
who and when is vaccination for HPV given?
MSM >45yrs
HIV +ve
11-13yr old F
complications of HPV?
SSC
adenocarcinoma
what causes gonorrhoea? features on gram stain?
neisseria gonorrhoea
gram -ve diplococcus
features of gonorrhoea in M and F?
M
- asymp
- dysuria
- mucopurulent urethral discharge
F
- asymp
- discharge
- dysuria
- pelvic/abdo pain
Ix for gonorrhoea? where is swab taken?
NAAT from
urethral/vulvovaginal/endocervical/pharyngeal/rectal
culture
Tx for gonorrhoea?
ceftriaxone and azithromycin IM
no sex for 7 days
does gonorrhoea have a test of cure and when?
yes
2wks after meds
what causes genital herpes?
HSV 1 + 2
pathology of herpes?
replicates in skin and moves to nerve endings
causes pain
settles in sacral root ganglion
can be reactivated
features of genital herpes?
blistering and ulceration pain dysuria discharge fever myalgia
Ix for herpes?
swab ulcer and PCR
Ix for HPV?
none (clinical diagnosis)
Tx for herpes?
acyclovir and pain relief
what usually causes genital candida infections?
candida albicans
what risk factors are there for candida infections?
antibios
high oestrogen
diabetes
immunocomp
features of candida infections?
itch
white vaginal discharge
Ix for candida infections?
clinical
Tx for candida infections?
clotrimazole (topical)
fluconazole (oral)
what causes bacterial vaginosis?
imbalance of vaginal bacteria
becomes alkaline
bacteria replaced with anaerobic species
features of bacterial vaginosis?
fish smell
itchy
bubbly discharge
M - spotty rash on penis
Ix for bacterial vaginosis?
swab
culture
microscopy - clue cells
whiff test
Tx for bacterial vaginosis?
FEMALES ONLY
metronidazole
what causes chlamydia?
chlamydia trachomatis
what serovars of chlamydia cause what?
A-C eye infection
D-K STI
L1-L2 lymphogranuloma venerum
features of chlamydia?
asymp dysuria discharge intermenstural/postcoital bleeding lower abdo pain
features of lymphogranuloma venerum?
rectal pain discharge bleeding tenesmus proctitis
Ix for chlamydia? where are swabs?
NAAT
vulvovaginal
first void urine (M)
rectal
Tx for chlamydia?
azithromycin
erythromycin if pregnant
for chlamydia, who gets test of cure? when?
pregnant
rectal infection
3 wks after
Tx for pubic lice?
malathion lotion
symptoms of acute bacterial prostatitis?
lower abdo pain perineal pain penile pain tender prostate UTI symptoms
how can acute bacterial prostatitis arise?
complication of UTI
usual infecting organisms in acute bacterial prostatitis?
e coli
chlamydia
gonorrhoea
tx for prostatis?
ciprofloxacin
what is trichomonas vaginalis?
single celled parasite
features of trichomonas vaginalis?
bubbly discharge
green
fish odour
strawberry cervix
Ix for trichomonas vaginalis?
microscopy
shows flagella
Tx for trichomonas vaginalis?
metronidazole
PID Tx?
IM ceftriazone
metronidazole
doxycycline