Infertility Flashcards

1
Q

causes of obstructive male infertility?

A

CF
chlamydia
vasectomy

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2
Q

in CF, what anatomical variant causes the infertility?

A

bilateral absence of vas deferens

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3
Q

normal testicular volume in adults?

A

12-25mls

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4
Q

Ix for male infertility?

A
semen analysis
endocrine profile
chromosome analysis
biopsy
testicular US
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5
Q

in people with CF, what form of artificial insemination is offered?

A

ICSI

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6
Q

what happens in ICSI?

A

sperm extracted from epididymis or testicular tissue

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7
Q

in ICIS, how is the place of sperm retrieval chosen?

A
if infertility is
obstructive (epididymis(
non obstructive (testicular tissue)
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8
Q

what form of artificial insemination can be used in those with HIV?

A

intra uterine insemination

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9
Q

how much alcohol can people undergoing AI Tx have?

A

<4 units a week

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10
Q

what BMI should people undergoing AI Tx have?

A

19-29

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11
Q

can people undergoing AI Tx smoke?

A

no

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12
Q

what must people undergoing AI Tx take?

A

0.4mg folic acid (until 12wks gestation)

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13
Q

what screening must people undergoing AI Tx have?

A

rubella
hep b
hep c
HIV

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14
Q

what are the steps of IVF?

A
down regulation
ovarian stimulation
oocyte collection
fertilisation
embryo transfer
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15
Q

what happens in down regulation?

A

GnRH puts women into menopause

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16
Q

what happens in ovarian stimulation?

A

HCG given to cause follicle development

17
Q

what happens in fertilisation?

A

blastocyst frozen at day 5

18
Q

what happens in embryo transfer?

A

embryo transferred
progesterone given
pregnancy test taken 16 days after oocyte collection

19
Q

features of ovarian hyperstimulation syndrome?

A
abdo pain
bloating
nausea
diarrhoea
SOB
20
Q

what hormone is used to assess ovarian reserve?

A

AMH

21
Q

who can get assisted conception Tx?

A

regular (2-3x a wk) unprotected sex for a year

2 yrs if no cause found