Antenatal Screening Flashcards
how to estimate due date?
+280
9 months and 7 days
what blood tests are done at booking?
Hb random blood glucose FBC ABO rhesus syphilis HIV Hep B
what other investigations are done?
urinalysis
BP
BMI
for trisomy 21, when and what are the three investigations that can be done?
bloods
amniocentesis
chorionic villus sampling
when is maternal anaemia screened for?
booking and 28 weeks
where is AFP produced?
the yolk sac
what is AFP used to screen for? why is it elevated in these cases?
spina bifida
gastroschisis
twins
-> increased exposure of fetal surfaces to amniotic fluid
when is Rh screening and doses given? why would women be given a dose?
booking
28wks
34wks
if she needed anti D prophylaxis due to being rhesus negative
if balanced, what genetic test can be used to find chromosome translocations?
aCGH
what is the name for a balanced and unbalanced translocation?
balanced - reciprocal
unbalanced - robertsonian
when can chorionic villus biopsy be done? what is miscarriage risk?
11.5wks
2%
when can amniocentesis be done from? what is the miscarriage risk?
16 wks
1%
when can fetal blood sampling be done?
18 wks
from biggest to smallest, what genetic Ix cover large areas of the gene to small?
chromosome analysis
aCGH
PCR
NGS
what immunity should it be ensured a pregnant women has?
rubella
what supplements should a pregnant women be taking?
iron (if anaemic)
folic acid (until 4wks)
vit D
when is the nuchal scan conducted? what is this for?
11-13
downs syndrome
when is the anomaly scan done?
18-20
when is the dating scan done? what is excluded here?
10-13
multiple pregnancy
what dates are further routine care check done, if the women is a primip?
25 wks and 31wks
if women is not a primip, when is second routine care check done?
28wks
when is a urine culture done to detect asympt bacteria?
8-12 wks
what are you looking for on anomaly scan?
brain malformations
cardiac problems
microcephaly
limb malformations
what and when is the combined test for down’s done?
10-13wks
nuchal thickness
beta HCG
PAPP-A
