Steroids, Leukotrienes And Muscarinic Antagonists Flashcards
What does cortisone do to the body
Response to stress
Suppress immune system
Increase blood sugar
Anti inflammatory
What are the physical properties of steroids?
White crystalline solid
Melting point 100 -250 degrees
Poorly soluble in water
What type of compounds are leukotrienes?
Fatty compounds
What are the two main mechanisms to inhibit leukotrienes?
Leukotriene antagonist
Inhibition leukotriene synthesis
What is the Wittig reaction?
Aldehyde/ketone + triphenyl phosphonium ylide goes to alkene
How does zileuton work?
Inhibitor of 5-lipocygenase to suppress leukotriene formation
How does theophylline work?
Non selective adenosine receptor antagonist inhibiting leukotriene synthesis
What are the different classes of steroids
Sex hormones
Cholesterol
Corticosteroid