Steroids, Leukotrienes And Muscarinic Antagonists Flashcards

1
Q

What does cortisone do to the body

A

Response to stress
Suppress immune system
Increase blood sugar
Anti inflammatory

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2
Q

What are the physical properties of steroids?

A

White crystalline solid

Melting point 100 -250 degrees

Poorly soluble in water

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3
Q

What type of compounds are leukotrienes?

A

Fatty compounds

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4
Q

What are the two main mechanisms to inhibit leukotrienes?

A

Leukotriene antagonist

Inhibition leukotriene synthesis

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5
Q

What is the Wittig reaction?

A

Aldehyde/ketone + triphenyl phosphonium ylide goes to alkene

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6
Q

How does zileuton work?

A

Inhibitor of 5-lipocygenase to suppress leukotriene formation

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7
Q

How does theophylline work?

A

Non selective adenosine receptor antagonist inhibiting leukotriene synthesis

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8
Q

What are the different classes of steroids

A

Sex hormones
Cholesterol
Corticosteroid

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