Immunology & Allergy Flashcards
What are the 4 main roles of immune organs and tissues?
Immunological reactants depot
Mobile defence force
Lymphocyte re circulation
Lymphoid tissue placed strategically
What is altered self in respect to clonal selection and expansion?
The ability to distinguish a foreign harmful antigenic threat from its self
Where are lymph nodes found?
At junctions of draining lymphatics
Where does lymph collect and which vein is used to transport it to the blood?
Collect in thoracic duct
Subclavian vein
What are IELs
Intraepithelial lymphocytes
What CD are Tc cells and Th cells
Tc - CD8
Th - CD4
Which interleukins cause allergy problems
IL 4 & IL 5
Which T helper cell is involved in allergy response?
Th 2
What are the 5 classes of immunoglobulin?
IgG, A, M, D, E
What are Fc receptors?
Specific receptors on cell surface of Ig
Where are the IgE receptors predominately found?
On basophils and mast cells
