Smooth Muscle Flashcards
1
Q
What does smooth muscle contraction require?
A
Calcium ions
2
Q
How can calcium ions be generated for smooth muscle contraction?
A
Influx across plasma membrane
Intercellular stores
3
Q
How does myosin bind to actin for smooth muscle contraction and relaxation
A
Calcium ion binds to calmodulin
This product activated MLCK
MLCK phosphorylates MLC
This phosphorylation caused actin to bind and contraction occurs
4
Q
What is needed for smooth muscle relaxation
A
cAMP
5
Q
What is used in vascular smooth muscle relaxation
A
NO
6
Q
What are the functional roles of smooth muscle
A
Regulate flow by varying tube diameter
Control flow by occluding tube
Walls of storage organ
Movement of large bulk
