Steroid hormone diseases Flashcards
1
Q
No steroid hormones
Marked salt excretion in urine; all patients have female genitalia
A
B-hydroxysteroid dehydrogenase deficiency
2
Q
Mutation in StAR
Nearly complete loss of steroid production
Alternate mutation of desmolase
A
Lipoid congenital adrenal hyperplasia
3
Q
Virtually no sex hormones or cortisol
Increased aldosterone
Sodium and fluid retention leading to hypertension
All patients have female genitalia
A
17-a-hydroxylase deficiency
4
Q
Most common form of congenital adrenal hyperplasia
No glucocorticoids or mineralocorticoids
Androgens overproduced
Most common cause of female hermaphroditism
A
21-a-hydroxylase deficiency
5
Q
Decreased cortisol, aldosterone, corticosterone
Increased deoxycorticosterone
A
11-B-hydroxylase deficiency
