Eukaryotic DNA polymerases Flashcards
1
Q
Contains primase
No proofreading capabilities
Multisubunit–primase synthesizes short RNA primer; polymerase extends it to synthesize DNA
A
Pol a
2
Q
Involved in gap-filling in DNA repair
No proofreading capabilities or ribonucleotide excision capabilities
A
Pol B
3
Q
Replicates mitochondrial DNA
Proofreads in 3–>5 direction
A
Pol y
4
Q
Elongates Okazaki fragments on lagging strand
Proofreads in 3–>5 direction (exonuclease activity)
A
Pol d
5
Q
Elongates leading strand
Proofreads in 3–>5 direction (exonuclease activity)
A
Pol E
6
Q
Elongates leading strand
Proofreads in 3–>5 direction (exonuclease activity)
A
Pol E
7
Q
Remove RNA primers
A
RNase H and FEN1
