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Biochem > Antibiotics that affect translation > Flashcards

Antibiotics that affect translation Flashcards

1
Q

Distorts 30S subunit

Only antibiotic to affect initiation

A

Streptomycin

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2
Q

Binds to 30S subunit, blocking entry of AA-tRNA to A side

A

Tetracycline

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3
Q

Inhibits peptidyltransferase

A

Chloramphenicol

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4
Q

Binds to 50S subunit, blocking translocation

A

Clindamycin

Erythromycin

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5
Q

Inactivates elongation factor, blocking translocation

A

Diphtheria toxin

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6
Q

May bind to E site and block translocation

A

Cycloheximide

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7
Q

AA-tRNA analogue, causes peptide chain termination

Only antibiotic to affect both prokaryotes and eukaryotes

A

Puromycin

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Biochem (29 decks)

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