Glucose Transporters Flashcards
1
Q
Found in most tissues
Basal transport
Km=5mM
Small Vmax
A
GLUT1
2
Q
Predominant in neurons
Basal transport
Km=1mM
Small Vmax
A
GLUT3
3
Q
Present in liver, pancreatic beta cells, and brush border
Km=15-20 mM
Higher Vmax
Affected by insulin
A
GLUT2
4
Q
Major insulin-responsive transporter
Specific to muscle and fat cells
Km=5 mM
A
GLUT4
5
Q
Present on apical brush border & in sperm
Specific for fructose
A
GLUT5
6
Q
Apical brush border
Specific for glucose
Secondary active transport
A
SGLT1
