Steriods Flashcards

1
Q

What are 5 Actions of Glucocorticoids?

A
  1. Metabolic
  2. Anti inflammatory
  3. Immunosuppressive
  4. CNS effects
  5. Mineralcorticoids
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2
Q

What are the 6 uses of Glucocorticoids?

A
  1. Anti inflammatory
  2. Immunosuppressive
  3. Addison’s disease
  4. Induce abortion last trimester
  5. Chemotherapy for malignant tumours
  6. Ketosis in cows
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3
Q

What are the 3 formulations of Glucocorticoids?

A

Oral, Injectable, Topical

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4
Q

What are the Oral routes of Glucocorticoids?

A

Prednisone, prednisolone, Vanectyl-P, dexamethasone

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5
Q

What re the Injectable routes of Glucocorticoids?

A

hydrocortisone, prednisone, methylprednisone, triamcinolone, flumethasone, betamethasone, dexamethasone, isoflupredone

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6
Q

What are the Topical routes of Glucocorticoids?

A

Hydrocortisone, bethmethasone, mixed w/ ABx

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7
Q

What are the short term toxicities of glucocorticoids?

A
  1. PU/PD
  2. increased susceptibility to infection
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8
Q

What are the long term toxicities of glucocorticoids?

A
  1. Iatrogenic Cushing’s
  2. Iatrogenic Addison’s
  3. Gastric ulceration
  4. Osteoporosis
  5. Pancreatitis
  6. Nephrotoxicity
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9
Q

What are the Actions of NSAIDs?

A
  1. Inhibition of PGE2
  2. Analgesic & anti-pyretic on brain
  3. Decrease platelet aggregation
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10
Q

What are the uses of NSAIDs?

A
  1. Analgesia
  2. Anti-pyretic
  3. Anti inflammatory
  4. Endo-toxic shock
  5. Anti-thrombotic
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11
Q

What are the 3 routes for NSAIDs

A

Oral, injectable, otic/opthalmic

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12
Q

What are the oral routes of NSAIDs?

A

Phenylbutazone, meclofenamic acid, piroxicam, ketoprofen, meloxicam, carprofen

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13
Q

What are the injectable routes of NSAIDs?

A

Phenylbutazone, meloxicam, tolfenamic acid

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14
Q

What are the Toxicities for NSAIDs?

A

Gastric irritation, ulceration, nephrotoxicity, can’t can’t metabolize & secrete as fast, hepatotoxicity, do not use on dogs and cats w/ acetaminophen, aspirin, or ibuprofen

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15
Q

What are the Actions of Antihistamines?

A
  1. Response to allergen
  2. Block histamine receptors
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16
Q

What are the uses of Antihistamines?

A

Felines asthma, allergies

17
Q

What are the Antihistamine drugs for dogs?

A

Chlorpheniramine, brompheniramine, hydroxyzine

18
Q

What are the Antihistamine drugs for cats?

A

Chlorpheniramine, clemastine, hydroxyzine

19
Q

What are the Toxicities for Antihistamines?

A

Sedation, nausea, vomiting

20
Q

What is DMSO?

A

Dimethyl Sulfoxide

21
Q

What are the uses of DMSO?

A

Anti inflammatory, soft tissue damage

22
Q

What are the routes of DMSO?

A

Liquid, gel, otic prep for dogs