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Pharmacy > AntiFungals & AntiVirals > Flashcards

AntiFungals & AntiVirals Flashcards

1
Q

What is the route of Amphotericin B?

A

IV

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2
Q

What are the Action/Uses of Amphotericin B?

A

Highly protein bound, limit penetration of CNS, bone, and eye

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3
Q

What are the Toxicities of Amphotericin B?

A

Nephrotoxic, do not combine with other nephrotoxic drugs, cats sensitive, GI, anemia

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4
Q

What is the route of Griseofulvin

A

Oral

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5
Q

What is the Action of Griseofulvin?

A

Fungistatic

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6
Q

What are the Toxicities of Griseofulvin?

A

GIT upset, Rare: hepatotoxic/photosensitization, cat/kitten more sensitive = anemia, neurotoxicity, anorexia, vomiting, teratogenic.

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7
Q

What are the Toxicities of Nystatin?

A

Rare side effects for topical

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8
Q

What are the Actions/Uses of Nystatin?

A

Yeast infections, (combined w/ other drugs)

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9
Q

Drugs under Imidazoles?

A

Enilconazole, Miconazole, Ketoconizole, Clotrimazole, Itraconazole, Econazole

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10
Q

What is the route of Enilconazole?

A

Topical

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11
Q

What are the Actions/Uses of Enilconazole?

A

Ringworm on dogs & horses

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12
Q

What is the Route of Nystatin?

A

Oral or Topical

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13
Q

What are the Toxicities of Enilconazole?

A

Not irritating, safe if accidentally ingested while bathing

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14
Q

What is the Route of Miconazole?

A

Topical

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15
Q

What are the Action/Uses of Miconazole?

A

Topical dermatophyte infections, some yeast

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16
Q

What are the toxicities of Miconazole?

A

None

17
Q

What is the Route of Ketoconazole?

A

Oral or Topical

18
Q

What is the Action/Uses of Ketoconazole?

A

Yeast, dermatophytes, some systemic infections

19
Q

What are the Toxicities of Ketoconazole?

A

oral-anorexia & vomiting, cats = liver damage, teratogenic, reversible lightening of hair

20
Q

What is the Route of Clotrimazole?

A

Topical or Otic

21
Q

What are the Action/Uses of Clotrimazole?

A

Topical Infections, yeast infection in ears

22
Q

What are the Toxicities of Clotrimazole?

A

None

23
Q

What is the Route of Itraconazole?

A

Oral (give with fatty meal)

24
Q

What is the Action/Uses of Itraconazole?

A

Systemic mycotic (internal fungal infection) in dogs and cats, better against Candida than Keto, aspergillus & dermatophytes

25
Q

What are the Toxicities of Itraconazole?

A

Teratogenic, GIT upset, hepatotoxicity, cutaneous rxns

26
Q

What is the Route of Econazole?

A

Topical

27
Q

What are the Action/Uses of Econazole?

A

Dermatophytes, yeasts, moulds

28
Q

What are the Toxicities of Econazole?

A

Well tolerated topically

29
Q

What is the Route of Interferon?

A

Oral, cutaneous

Pharmacy (15 decks)

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