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BDI > Staphylococcus Aureus > Flashcards

Staphylococcus Aureus Flashcards

1
Q

Catalase test

A

+, cleaves H2O2 into H2O and O2

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2
Q

Morphology, gram stain

A

Gram _ cocci in clusters

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3
Q

Coagulase test

A

Coagulase +
Coagulase binds fibrogen and activates final stages of coagulation

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4
Q

Blood agar

A

Beta hemolysis

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5
Q

Most common site of colonization by S aureus

A

Nares

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6
Q

S aureus is the most common cause of

A

Endocarditis
Nosocomial infection
Surgical site infection
Cellulitis
Osteomyelitis
Septic arthritis
Also a common cause of bacteremia, nosocomial pneumonia, foodborne illness, implant infection, abscess

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7
Q

S aureus is a prominent cause for

A

Skin and soft tissue infections
Impetigo
Folliculitis
Furuncles
Carbuncles
Paronychia
Cellulitis
Erysipelas

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8
Q

S aureus release

A

Pus

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9
Q

S aureus bacteremia

A

3rd most common cause of nosocomial bacteremia
Mortality due to age, underlying disease, antibiotic resistance

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10
Q

S aureus live in

A

Macrophages facilitating metastasis

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11
Q

Staphylococcal diseases caused by metastatic seeding

A

Osteomyelitis
Endocarditis
Kidney abscesses

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12
Q

Staphylococcal pneumoniae

A

Community acquired
Ventilator associated
Due to colonization of the respiratory tract
Secondary bacteremia is common

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13
Q

Staphylococcal extracellular enzymes

A

Catalase counteracts oxygen radicals generated by PMNs and staphylococcal respiration
Coagulase binds to prothrombin facilitating survival unplugged it and is required for an abscess to form
Hyaluronidase breaks down hyaluronic acids
DNAase, lipase, protease, staphylokinase breaks down cellular basement membranes
hemolysis, alpha-toxin, leukocidin lyses RBC and WBC

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14
Q

TSST1

A

Staphylococcal toxic shock syndrome toxin

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15
Q

Scalded skin syndrome

A

Staphylococcal toxin mediated disruption of desmosomes within epithelium

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16
Q

Food poisoning

A

Staphylococcal toxin mediated-enterotoxins stimulate parasympathetic nervous system and CNS emetic

17
Q

Staphylococcal food poisoning

A

2nd most common cause of food borne disease (processed meats, custard filled pastry, potato salad, egg salad)
Abrupt onset and spontaneous resolution in 8-12 hours

18
Q

MRSA

A

Methicillin resistant Staphylococcus aureus
Methacillin=oxacillin
MecA: Acquisition of new PBP called PBP2A that does not bind oxacillin and is therefor resistant

19
Q

Coagulase negative Staphylococci

A

S epidermis: prosthetic device infection, nosocomial bacteremia
S saprophyticus: UTI
S haemolyticus: vancomycin resistant
S lugduneensis: more virulent, skin and soft tissue infection (SSTI)

20
Q

S saprophyticus

A

2nd most common cause of UTI in young, healthy, sexually active women
Adheres to uroepithelial cells
Produces urease

BDI (18 decks)

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